Can near-infrared spectroscopy identify the severity of shock in trauma patients?

Bruce A. Crookes, Stephen M. Cohn, Scott Bloch, Jose Amortegui, Ronald Manning, Pam Li, Matthew S. Proctor, Ali Hallal, Lorne H. Blackbourne, Robert Benjamin, Dror Soffer, Fahim Habib, Carl I. Schulman, Robert Duncan, Kenneth G. Proctor, Juan Carlos Puyana, John A. Morris, Martin A. Schreiber, Rao R. Ivatury, CansfieldThomas A. Santora

Research output: Contribution to journalArticle

153 Citations (Scopus)

Abstract

Background: Our recent experimental study showed that peripheral muscle tissue oxygen saturation (StO2), determined noninvasively by near-infrared spectroscopy (NAS), was more reliable than systemic hemodynamics or invasive oxygenation variables as an index of traumatic shock. The purpose of this study was to establish the normal range of thenar muscle StO2 in humans and the relationship between shock state and StO2 in trauma patients. Methods: This was a prospective, nonrandomized, observational, descriptive study in normal human volunteers (n = 707) and patients admitted to the resuscitation area of our Level I trauma center (n = 150). To establish a normal StO2 range, an NIRS probe was applied to the thenar eminence of volunteers (normals). Subsequently, in a group of trauma patients, an NIRS probe was applied to UK thenar eminence and data were collected and stored for offline analysis. StO2 monitoring was performed continuously and noninvasively, and values were recorded at 2-minuie intervals. Five moribund trauma patients were excluded. Members of our trauma faculty, blinded to StO2 values, classified each patient into one of four groups (no shock, mild shock, moderate shock, and severe shock) using conventional physiologic parameters. Results: Mean ± SD thenar StO2 values for each group were as follows: normals, 87 ± 6% (n = 707); no shock, 83 ± 10% (n = 85); mild shock, 83 ± 10% (n = 19); moderate shock, 80 ± 12% (n = 14); and severe shock, 45 ± 26% (n = 14). The thenar StO2 values clearly discriminated the normals or no shock patients and the patients with severe shock (p < 0.05). Conclusion: Decreased thenar muscle tissue oxygen saturation reflects the presence of severe hypoperfusion and near-infrared spectroscopy may be a novel method for rapidly and noninvasively assessing changes in tissue dysoxia.

Original languageEnglish (US)
Pages (from-to)806-816
Number of pages11
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume58
Issue number4
DOIs
StatePublished - Apr 2005

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Near-Infrared Spectroscopy
Shock
Wounds and Injuries
Muscles
Healthy Volunteers
Reference Values
Traumatic Shock
Oxygen
Trauma Centers
Resuscitation
Observational Studies
Hemodynamics

Keywords

  • Near-infrared spectroscopy
  • Oxygen delivery
  • Resuscitation endpoints
  • Tissue oxygen saturation

ASJC Scopus subject areas

  • Surgery

Cite this

Can near-infrared spectroscopy identify the severity of shock in trauma patients? / Crookes, Bruce A.; Cohn, Stephen M.; Bloch, Scott; Amortegui, Jose; Manning, Ronald; Li, Pam; Proctor, Matthew S.; Hallal, Ali; Blackbourne, Lorne H.; Benjamin, Robert; Soffer, Dror; Habib, Fahim; Schulman, Carl I.; Duncan, Robert; Proctor, Kenneth G.; Puyana, Juan Carlos; Morris, John A.; Schreiber, Martin A.; Ivatury, Rao R.; Cansfield; Santora, Thomas A.

In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 58, No. 4, 04.2005, p. 806-816.

Research output: Contribution to journalArticle

Crookes, BA, Cohn, SM, Bloch, S, Amortegui, J, Manning, R, Li, P, Proctor, MS, Hallal, A, Blackbourne, LH, Benjamin, R, Soffer, D, Habib, F, Schulman, CI, Duncan, R, Proctor, KG, Puyana, JC, Morris, JA, Schreiber, MA, Ivatury, RR, Cansfield & Santora, TA 2005, 'Can near-infrared spectroscopy identify the severity of shock in trauma patients?', Journal of Trauma - Injury, Infection and Critical Care, vol. 58, no. 4, pp. 806-816. https://doi.org/10.1097/01.TA.0000158269.68409.1C
Crookes, Bruce A. ; Cohn, Stephen M. ; Bloch, Scott ; Amortegui, Jose ; Manning, Ronald ; Li, Pam ; Proctor, Matthew S. ; Hallal, Ali ; Blackbourne, Lorne H. ; Benjamin, Robert ; Soffer, Dror ; Habib, Fahim ; Schulman, Carl I. ; Duncan, Robert ; Proctor, Kenneth G. ; Puyana, Juan Carlos ; Morris, John A. ; Schreiber, Martin A. ; Ivatury, Rao R. ; Cansfield ; Santora, Thomas A. / Can near-infrared spectroscopy identify the severity of shock in trauma patients?. In: Journal of Trauma - Injury, Infection and Critical Care. 2005 ; Vol. 58, No. 4. pp. 806-816.
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abstract = "Background: Our recent experimental study showed that peripheral muscle tissue oxygen saturation (StO2), determined noninvasively by near-infrared spectroscopy (NAS), was more reliable than systemic hemodynamics or invasive oxygenation variables as an index of traumatic shock. The purpose of this study was to establish the normal range of thenar muscle StO2 in humans and the relationship between shock state and StO2 in trauma patients. Methods: This was a prospective, nonrandomized, observational, descriptive study in normal human volunteers (n = 707) and patients admitted to the resuscitation area of our Level I trauma center (n = 150). To establish a normal StO2 range, an NIRS probe was applied to the thenar eminence of volunteers (normals). Subsequently, in a group of trauma patients, an NIRS probe was applied to UK thenar eminence and data were collected and stored for offline analysis. StO2 monitoring was performed continuously and noninvasively, and values were recorded at 2-minuie intervals. Five moribund trauma patients were excluded. Members of our trauma faculty, blinded to StO2 values, classified each patient into one of four groups (no shock, mild shock, moderate shock, and severe shock) using conventional physiologic parameters. Results: Mean ± SD thenar StO2 values for each group were as follows: normals, 87 ± 6{\%} (n = 707); no shock, 83 ± 10{\%} (n = 85); mild shock, 83 ± 10{\%} (n = 19); moderate shock, 80 ± 12{\%} (n = 14); and severe shock, 45 ± 26{\%} (n = 14). The thenar StO2 values clearly discriminated the normals or no shock patients and the patients with severe shock (p < 0.05). Conclusion: Decreased thenar muscle tissue oxygen saturation reflects the presence of severe hypoperfusion and near-infrared spectroscopy may be a novel method for rapidly and noninvasively assessing changes in tissue dysoxia.",
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T1 - Can near-infrared spectroscopy identify the severity of shock in trauma patients?

AU - Crookes, Bruce A.

AU - Cohn, Stephen M.

AU - Bloch, Scott

AU - Amortegui, Jose

AU - Manning, Ronald

AU - Li, Pam

AU - Proctor, Matthew S.

AU - Hallal, Ali

AU - Blackbourne, Lorne H.

AU - Benjamin, Robert

AU - Soffer, Dror

AU - Habib, Fahim

AU - Schulman, Carl I.

AU - Duncan, Robert

AU - Proctor, Kenneth G.

AU - Puyana, Juan Carlos

AU - Morris, John A.

AU - Schreiber, Martin A.

AU - Ivatury, Rao R.

AU - Cansfield,

AU - Santora, Thomas A.

PY - 2005/4

Y1 - 2005/4

N2 - Background: Our recent experimental study showed that peripheral muscle tissue oxygen saturation (StO2), determined noninvasively by near-infrared spectroscopy (NAS), was more reliable than systemic hemodynamics or invasive oxygenation variables as an index of traumatic shock. The purpose of this study was to establish the normal range of thenar muscle StO2 in humans and the relationship between shock state and StO2 in trauma patients. Methods: This was a prospective, nonrandomized, observational, descriptive study in normal human volunteers (n = 707) and patients admitted to the resuscitation area of our Level I trauma center (n = 150). To establish a normal StO2 range, an NIRS probe was applied to the thenar eminence of volunteers (normals). Subsequently, in a group of trauma patients, an NIRS probe was applied to UK thenar eminence and data were collected and stored for offline analysis. StO2 monitoring was performed continuously and noninvasively, and values were recorded at 2-minuie intervals. Five moribund trauma patients were excluded. Members of our trauma faculty, blinded to StO2 values, classified each patient into one of four groups (no shock, mild shock, moderate shock, and severe shock) using conventional physiologic parameters. Results: Mean ± SD thenar StO2 values for each group were as follows: normals, 87 ± 6% (n = 707); no shock, 83 ± 10% (n = 85); mild shock, 83 ± 10% (n = 19); moderate shock, 80 ± 12% (n = 14); and severe shock, 45 ± 26% (n = 14). The thenar StO2 values clearly discriminated the normals or no shock patients and the patients with severe shock (p < 0.05). Conclusion: Decreased thenar muscle tissue oxygen saturation reflects the presence of severe hypoperfusion and near-infrared spectroscopy may be a novel method for rapidly and noninvasively assessing changes in tissue dysoxia.

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KW - Near-infrared spectroscopy

KW - Oxygen delivery

KW - Resuscitation endpoints

KW - Tissue oxygen saturation

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