Calorie Restriction as a Probe for Understanding Neuroendocrine Involvement in the Aging Processes

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The notions that age-related changes in the neuroendocrine system partly account for hormonal changes during aging and that the neuroendocrine system thereby contributes to the development of the senescent phenotype are widely accepted. Less attention has been given to the possibility that the neuroendocrine system can play a role in the retardation of aging. The objective of this paper is to present evidence that the neuroendocrine system contributes to the retardation of aging by food restriction by orchestrating the hormonal changes that are associated with chronic caloric restriction. Relatively little is known about the characteristics of the neuroendocrine system of the chronically food-restricted organism. The evidence that this system may play a central role in mediating the life-extending action of food restriction argues for further study of neuroendocrine function in the food-restricted animal.

Original languageEnglish (US)
Pages (from-to)204-209
Number of pages6
JournalNeuroprotocols
Volume4
Issue number3
DOIs
StatePublished - Jun 1994

Fingerprint

Neurosecretory Systems
Food
Caloric Restriction
Phenotype

Cite this

Calorie Restriction as a Probe for Understanding Neuroendocrine Involvement in the Aging Processes. / Nelson, James F.

In: Neuroprotocols, Vol. 4, No. 3, 06.1994, p. 204-209.

Research output: Contribution to journalArticle

@article{b554b87d44d84a84a306c8aab913ac20,
title = "Calorie Restriction as a Probe for Understanding Neuroendocrine Involvement in the Aging Processes",
abstract = "The notions that age-related changes in the neuroendocrine system partly account for hormonal changes during aging and that the neuroendocrine system thereby contributes to the development of the senescent phenotype are widely accepted. Less attention has been given to the possibility that the neuroendocrine system can play a role in the retardation of aging. The objective of this paper is to present evidence that the neuroendocrine system contributes to the retardation of aging by food restriction by orchestrating the hormonal changes that are associated with chronic caloric restriction. Relatively little is known about the characteristics of the neuroendocrine system of the chronically food-restricted organism. The evidence that this system may play a central role in mediating the life-extending action of food restriction argues for further study of neuroendocrine function in the food-restricted animal.",
author = "Nelson, {James F}",
year = "1994",
month = "6",
doi = "10.1006/ncmn.1994.1026",
language = "English (US)",
volume = "4",
pages = "204--209",
journal = "Neuroprotocols",
issn = "1058-6741",
publisher = "Academic Press Inc.",
number = "3",

}

TY - JOUR

T1 - Calorie Restriction as a Probe for Understanding Neuroendocrine Involvement in the Aging Processes

AU - Nelson, James F

PY - 1994/6

Y1 - 1994/6

N2 - The notions that age-related changes in the neuroendocrine system partly account for hormonal changes during aging and that the neuroendocrine system thereby contributes to the development of the senescent phenotype are widely accepted. Less attention has been given to the possibility that the neuroendocrine system can play a role in the retardation of aging. The objective of this paper is to present evidence that the neuroendocrine system contributes to the retardation of aging by food restriction by orchestrating the hormonal changes that are associated with chronic caloric restriction. Relatively little is known about the characteristics of the neuroendocrine system of the chronically food-restricted organism. The evidence that this system may play a central role in mediating the life-extending action of food restriction argues for further study of neuroendocrine function in the food-restricted animal.

AB - The notions that age-related changes in the neuroendocrine system partly account for hormonal changes during aging and that the neuroendocrine system thereby contributes to the development of the senescent phenotype are widely accepted. Less attention has been given to the possibility that the neuroendocrine system can play a role in the retardation of aging. The objective of this paper is to present evidence that the neuroendocrine system contributes to the retardation of aging by food restriction by orchestrating the hormonal changes that are associated with chronic caloric restriction. Relatively little is known about the characteristics of the neuroendocrine system of the chronically food-restricted organism. The evidence that this system may play a central role in mediating the life-extending action of food restriction argues for further study of neuroendocrine function in the food-restricted animal.

UR - http://www.scopus.com/inward/record.url?scp=38149146108&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38149146108&partnerID=8YFLogxK

U2 - 10.1006/ncmn.1994.1026

DO - 10.1006/ncmn.1994.1026

M3 - Article

AN - SCOPUS:38149146108

VL - 4

SP - 204

EP - 209

JO - Neuroprotocols

JF - Neuroprotocols

SN - 1058-6741

IS - 3

ER -