Calcium and vitamin D modulate mouse colon epithelial proliferation and growth characteristics of a human colon tumor cell line

Michael J Wargovich, P. H. Lointier

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

The role of calcium and vitamin D in the prevention of colorectal cancer is only now being investigated at the organismal, cellular, and molecular biologic levels. Recent epidemiologic studies have supported the hypothesis that dietary calcium and vitamin D may be related to a reduced risk for colon cancer. The evidence from laboratory investigations in animals and in cell culture also indicate a possible preventative effect. Addition of calcium and vitamin D to the roster of developmental cancer chemopreventive agents for further research is warranted.

Original languageEnglish (US)
Pages (from-to)472-477
Number of pages6
JournalCanadian Journal of Physiology and Pharmacology
Volume65
Issue number3
StatePublished - 1987
Externally publishedYes

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Tumor Cell Line
Vitamin D
Colon
Calcium
Growth
Dietary Calcium
Colonic Neoplasms
Epidemiologic Studies
Colorectal Neoplasms
Cell Culture Techniques
Research
Neoplasms

ASJC Scopus subject areas

  • Physiology
  • Pharmacology

Cite this

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