Bromophycolides C-I from the Fijian red alga Callophycus serratus

Julia Kubanek; Anne C. Prusak; Terry W. Snell; Rachel A. Giese; Craig R. Fairchild; William Aalbersberg; Mark E. Hay

doi:10.1021/np050463o

Bromophycolides C-I from the Fijian red alga Callophycus serratus

Julia Kubanek, Anne C. Prusak, Terry W. Snell, Rachel A. Giese, Craig R. Fairchild, William Aalbersberg, Mark E. Hay

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines.

Original language	English (US)
Pages (from-to)	731-735
Number of pages	5
Journal	Journal of Natural Products
Volume	69
Issue number	5
DOIs	https://doi.org/10.1021/np050463o
State	Published - May 2006
Externally published	Yes

ASJC Scopus subject areas

Drug Discovery
Analytical Chemistry
Molecular Medicine
Complementary and alternative medicine
Pharmacology
Pharmaceutical Science
Organic Chemistry

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10.1021/np050463o

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title = "Bromophycolides C-I from the Fijian red alga Callophycus serratus",

abstract = "Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines.",

author = "Julia Kubanek and Prusak, {Anne C.} and Snell, {Terry W.} and Giese, {Rachel A.} and Fairchild, {Craig R.} and William Aalbersberg and Hay, {Mark E.}",

year = "2006",

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language = "English (US)",

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AU - Kubanek, Julia

AU - Prusak, Anne C.

AU - Snell, Terry W.

AU - Giese, Rachel A.

AU - Fairchild, Craig R.

AU - Aalbersberg, William

AU - Hay, Mark E.

PY - 2006/5

Y1 - 2006/5

N2 - Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines.

AB - Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines.

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JO - Journal of Natural Products

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Bromophycolides C-I from the Fijian red alga Callophycus serratus

Abstract

ASJC Scopus subject areas

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