Efforts to breed large numbers of marmosets and tamarins (Family Callitrichidae) for biomedical research began in the 1960s. 1 - 3 The species most commonly used and bred included the cotton-top tamarin (Saguinus oedipus), the saddle-backed tamarin (S. fuscicollis), the white-lipped tamarin (S. mystax), and the common marmoset (Callithrix jacchus). Breeding efforts intensified in the 1970s because the animals became less readily available from the wild and researchers desired animals that were of known age and parasite-free. Successful captive breeding of the cotton-top tamarin became particularly crucial as this species was declared endangered by its country of origin, Colombia, in 1972 and then by the U.S. in 1976. 4 Because of its endangered species status, use of the cotton-top tamarin as a general research resource in fields such as virology was reduced in the 1970s; however, this species was at this point recognized as a unique biomedical resource for the study of colon cancer, given its propensity to develop this important human cancer spontaneously.
|Original language||English (US)|
|Title of host publication||A Primate Model for the Study of Colitis and Colonic Carcinoma the Cotton-Top Tamarin (Saguinus oedipus)|
|Number of pages||10|
|ISBN (Print)||0849353637, 9781315890319|
|State||Published - Jan 1 2018|
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