Branching point effects on the passive properties of the cerebellar granule cell axon

Octavian D. Mocanu, Joan Oliver, Fidel Santamaría, James M. Bower

Research output: Contribution to journalConference articlepeer-review

3 Scopus citations


This paper describes a mathematical model of the axon of the cerebellar granule cell as it ascends into the molecular layer and branches into its two parallel fiber segments. We present a theoretical and computational analysis of the input resistance at the branching point and the degree of signal attenuation between the ascending segment of the axon and the parallel fibers. The results suggest considerable passive signal decay in this branch point. If correct, this result has important implications for cerebellar function, as granule cell activation would be expected to always propagate in the ascending but not necessarily the parallel fiber segments of the same axon. (C) 2000 Elsevier Science B.V. All rights reserved.

Original languageEnglish (US)
Pages (from-to)207-212
Number of pages6
StatePublished - Jun 2000
EventThe 8th Annual Computational Neuroscience Meeting (CNS'99) - Pittsburgh, PA, USA
Duration: Jul 18 1999Jul 22 1999


  • Ascending segment
  • Branching point
  • Cerebellar granule cell
  • Input conductance
  • Parallel fiber
  • Relative attenuation rate

ASJC Scopus subject areas

  • Computer Science Applications
  • Cognitive Neuroscience
  • Artificial Intelligence


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