Brain metastases from cervical cancer - A short review

Byron C. Branch, James M Henry, Giacomo G. Vecil

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Aims and background. Brain metastases from cervical cancer are extremely rare yet local recurrence and systemic spread is fairly common. The role of surgical resection and CNS screening for this pathology was interrogated from a review of the literature.

Clinical experience. We present a case of a single brain metastasis that originated from the cervix and describe chronologically the spread of the disease with pathological confirmations.

Review. Following an extensive English literature search, which only yielded 59 reported cases (n = 60 including the present case), we extrapolated basic trends regarding the demographics, pathophysiology, and treatment that portended a longer survival. Despite treatment, the majority of patients do not survive past 1 year from diagnosis of intracranial metastasis. A trend towards prolonged survival was observed among patients who received surgical resection of the brain metastasis.

Conclusions. Cervical carcinoma has been documented to metastasize to the brain, and this may occur via initial seeding of the lungs. Surgical resection and CNS screening may have beneficial roles in the management of metastatic cervical carcinoma.

Original languageEnglish (US)
Pages (from-to)e171-e179
JournalTumori
Volume100
Issue number5
StatePublished - Sep 1 2014

Fingerprint

Uterine Cervical Neoplasms
Neoplasm Metastasis
Brain
Carcinoma
Literature
Survival
Cervix Uteri
Demography
Pathology
Recurrence
Lung
Therapeutics

Keywords

  • Brain
  • Cervical cancer
  • Metastasis
  • Surgical resection.
  • Survival

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

Cite this

Branch, B. C., Henry, J. M., & Vecil, G. G. (2014). Brain metastases from cervical cancer - A short review. Tumori, 100(5), e171-e179.

Brain metastases from cervical cancer - A short review. / Branch, Byron C.; Henry, James M; Vecil, Giacomo G.

In: Tumori, Vol. 100, No. 5, 01.09.2014, p. e171-e179.

Research output: Contribution to journalArticle

Branch, BC, Henry, JM & Vecil, GG 2014, 'Brain metastases from cervical cancer - A short review', Tumori, vol. 100, no. 5, pp. e171-e179.
Branch BC, Henry JM, Vecil GG. Brain metastases from cervical cancer - A short review. Tumori. 2014 Sep 1;100(5):e171-e179.
Branch, Byron C. ; Henry, James M ; Vecil, Giacomo G. / Brain metastases from cervical cancer - A short review. In: Tumori. 2014 ; Vol. 100, No. 5. pp. e171-e179.
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