Borderline personality features possibly related to cingulate and orbitofrontal cortices dysfunction due to schizencephaly

Felipe Filardi da Rocha; Leandro Malloy-Diniz; Karla Cristhina Alves de Sousa; Hugo Alejandro Cano Prais; Humberto Correa; Antonio Lucio Teixeira

doi:10.1016/j.clineuro.2007.12.009

Borderline personality features possibly related to cingulate and orbitofrontal cortices dysfunction due to schizencephaly

Felipe Filardi da Rocha
, Leandro Malloy-Diniz
, Karla Cristhina Alves de Sousa
, Hugo Alejandro Cano Prais
, Humberto Correa
, Antonio Lucio Teixeira

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with prominent borderline features and compromise of executive functions, decision-making and attention. We hypothesize that the personality disorder of our patient could be related to cingulate cortex lesion and secondary orbitofrontal cortex dysfunction associated with schizencephaly.

Original language	English (US)
Pages (from-to)	396-399
Number of pages	4
Journal	Clinical Neurology and Neurosurgery
Volume	110
Issue number	4
DOIs	https://doi.org/10.1016/j.clineuro.2007.12.009
State	Published - Apr 2008
Externally published	Yes

Keywords

Borderline personality
Cingulate cortex
Impulsivity
Orbitofrontal cortex
Schizencephaly

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1016/j.clineuro.2007.12.009

Cite this

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abstract = "Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with prominent borderline features and compromise of executive functions, decision-making and attention. We hypothesize that the personality disorder of our patient could be related to cingulate cortex lesion and secondary orbitofrontal cortex dysfunction associated with schizencephaly.",

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AU - da Rocha, Felipe Filardi

AU - Malloy-Diniz, Leandro

AU - de Sousa, Karla Cristhina Alves

AU - Prais, Hugo Alejandro Cano

AU - Correa, Humberto

AU - Teixeira, Antonio Lucio

PY - 2008/4

Y1 - 2008/4

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AB - Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with prominent borderline features and compromise of executive functions, decision-making and attention. We hypothesize that the personality disorder of our patient could be related to cingulate cortex lesion and secondary orbitofrontal cortex dysfunction associated with schizencephaly.

KW - Borderline personality

KW - Cingulate cortex

KW - Impulsivity

KW - Orbitofrontal cortex

KW - Schizencephaly

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Borderline personality features possibly related to cingulate and orbitofrontal cortices dysfunction due to schizencephaly

Abstract

Keywords

ASJC Scopus subject areas

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