BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions

R. B. Markowitz, B. A. Eaton, M. F. Kubik, D. Latorra, J. A. McGregor, W. S. Dynan

Research output: Contribution to journalComment/debate

119 Scopus citations

Abstract

Twenty-three BK virus and JC virus DNA samples obtained from urine of pregnant women had almost exclusively archetypal transcriptional control regions. Rearrangements characteristic of laboratory strains are apparently not required for reactivation in humans. Unexpectedly, alignment shows that many elements identified previously in the BK virus enhancer are conserved in the JC virus archetype.

Original languageEnglish (US)
Pages (from-to)4515-4519
Number of pages5
JournalJournal of Virology
Volume65
Issue number8
StatePublished - Jan 1 1991

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ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Cite this

Markowitz, R. B., Eaton, B. A., Kubik, M. F., Latorra, D., McGregor, J. A., & Dynan, W. S. (1991). BK virus and JC virus shed during pregnancy have predominantly archetypal regulatory regions. Journal of Virology, 65(8), 4515-4519.