Biopsychosocial predictors of fatigue in chronic hepatitis C

Robin C. Hilsabeck, Tarek I. Hassanein, William Perry

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Original languageEnglish
Pages (from-to)173-178
Number of pages6
JournalJournal of Psychosomatic Research
Volume58
Issue number2
DOIs
StatePublished - Feb 2005
Externally publishedYes

Fingerprint

Chronic Hepatitis C
Fatigue
Depression
Self-Help Groups
Medical Records
Antiviral Agents
Counseling
Fibrosis
Regression Analysis
Quality of Life
Demography
Therapeutics
Research

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

Cite this

Biopsychosocial predictors of fatigue in chronic hepatitis C. / Hilsabeck, Robin C.; Hassanein, Tarek I.; Perry, William.

In: Journal of Psychosomatic Research, Vol. 58, No. 2, 02.2005, p. 173-178.

Research output: Contribution to journalArticle

Hilsabeck, Robin C. ; Hassanein, Tarek I. ; Perry, William. / Biopsychosocial predictors of fatigue in chronic hepatitis C. In: Journal of Psychosomatic Research. 2005 ; Vol. 58, No. 2. pp. 173-178.
@article{f740d3a799474c10a51cbdd5c6fd6454,
title = "Biopsychosocial predictors of fatigue in chronic hepatitis C",
abstract = "Objective: The objective of this study was to investigate the relationship of biopsychosocial variables to fatigue in patients with chronic hepatitis C (CHC) with the goal of identifying areas of possible intervention. Method: Ninety-four patients with CHC not on antiviral therapy completed a demographic questionnaire and measures of fatigue, health-related quality of life, and depression. Fibrosis stage and relevant medical information were obtained from medical records. Results: A stepwise multiple regression analysis revealed that the most significant predictor of fatigue was poor social functioning, followed by poor physical functioning, greater depression, and female gender. Together, these variables accounted for 68{\%} of the total variance in fatigue. Discussion: Study findings suggest that treatment strategies for fatigue in patients with CHC should focus on increasing social functioning in addition to improving physical functioning and decreasing depressive symptoms. Research investigating the effectiveness of interventions targeting social functioning, such as support groups and supportive counseling, is recommended.",
keywords = "Chronic illness, Depression, Fatigue, Gender differences, Hepatitis C, Social support",
author = "Hilsabeck, {Robin C.} and Hassanein, {Tarek I.} and William Perry",
year = "2005",
month = "2",
doi = "10.1016/j.jpsychores.2004.07.003",
language = "English",
volume = "58",
pages = "173--178",
journal = "Journal of Psychosomatic Research",
issn = "0022-3999",
publisher = "Elsevier Inc.",
number = "2",

}

TY - JOUR

T1 - Biopsychosocial predictors of fatigue in chronic hepatitis C

AU - Hilsabeck, Robin C.

AU - Hassanein, Tarek I.

AU - Perry, William

PY - 2005/2

Y1 - 2005/2

N2 - Objective: The objective of this study was to investigate the relationship of biopsychosocial variables to fatigue in patients with chronic hepatitis C (CHC) with the goal of identifying areas of possible intervention. Method: Ninety-four patients with CHC not on antiviral therapy completed a demographic questionnaire and measures of fatigue, health-related quality of life, and depression. Fibrosis stage and relevant medical information were obtained from medical records. Results: A stepwise multiple regression analysis revealed that the most significant predictor of fatigue was poor social functioning, followed by poor physical functioning, greater depression, and female gender. Together, these variables accounted for 68% of the total variance in fatigue. Discussion: Study findings suggest that treatment strategies for fatigue in patients with CHC should focus on increasing social functioning in addition to improving physical functioning and decreasing depressive symptoms. Research investigating the effectiveness of interventions targeting social functioning, such as support groups and supportive counseling, is recommended.

AB - Objective: The objective of this study was to investigate the relationship of biopsychosocial variables to fatigue in patients with chronic hepatitis C (CHC) with the goal of identifying areas of possible intervention. Method: Ninety-four patients with CHC not on antiviral therapy completed a demographic questionnaire and measures of fatigue, health-related quality of life, and depression. Fibrosis stage and relevant medical information were obtained from medical records. Results: A stepwise multiple regression analysis revealed that the most significant predictor of fatigue was poor social functioning, followed by poor physical functioning, greater depression, and female gender. Together, these variables accounted for 68% of the total variance in fatigue. Discussion: Study findings suggest that treatment strategies for fatigue in patients with CHC should focus on increasing social functioning in addition to improving physical functioning and decreasing depressive symptoms. Research investigating the effectiveness of interventions targeting social functioning, such as support groups and supportive counseling, is recommended.

KW - Chronic illness

KW - Depression

KW - Fatigue

KW - Gender differences

KW - Hepatitis C

KW - Social support

UR - http://www.scopus.com/inward/record.url?scp=17044376190&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=17044376190&partnerID=8YFLogxK

U2 - 10.1016/j.jpsychores.2004.07.003

DO - 10.1016/j.jpsychores.2004.07.003

M3 - Article

C2 - 15820845

AN - SCOPUS:17044376190

VL - 58

SP - 173

EP - 178

JO - Journal of Psychosomatic Research

JF - Journal of Psychosomatic Research

SN - 0022-3999

IS - 2

ER -