Biomarkers of maternal and fetal exposure to organochlorine pesticides measured in pregnant hispanic women from brownsville, texas

Ken Sexton, Jennifer J. Salinas, Thomas J. Mcdonald, Rose M.Z. Gowen, Rebecca P. Miller, Joseph B. McCormick, Susan P. Fisher-Hoch

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Biomarkers of organochlorine pesticides were measured in both venous and umbilical cord blood from 35 pregnant Hispanic women living in Brownsville, Texas, USA. Gas chromatography with an electron capture detector was used to analyze specimens for 30 individual pesticides or their metabolites. Results indicate that blood concentrations were relatively low for most individual compounds, but that high-end (upper 10th percentile) values for total DDT were comparatively high. Although health effects associated with measured blood concentrations are uncertain, there is concern that fetal exposure to low levels of these OC compounds, either individually or in combination, might contribute to subsequent health problems, including neurodevelopmental effects, cancer, endocrine disruption, obesity and diabetes.

Original languageEnglish (US)
Pages (from-to)237-248
Number of pages12
JournalInternational Journal of Environmental Research and Public Health
Volume10
Issue number1
DOIs
StatePublished - Jan 2013

Keywords

  • Biomarkers
  • Fetal exposure
  • Maternal exposure
  • Organochlorine pesticides

ASJC Scopus subject areas

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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