Biomarker measurements of prenatal exposure to polychlorinated biphenyls (Pcb) in umbilical cord blood from postpartum hispanic women in Brownsville, Texas

Ken Sexton, Jennifer J. Salinas, Thomas J. McDonald, Rose M.Z. Gowen, Rebecca P. Miller, Joseph B. McCormick, Susan P. Fisher-Hoch

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Biomarkers of polychlorinated biphenyls (PCB) were measured in both maternal and umbilical cord blood from 35 pregnant Hispanic women living in Brownsville, TX. Gas chromatography with an electron capture detector (GC/ECD) was used to analyze for 22 PCB analytes. Results indicated that both pregnant mothers and their fetuses were exposed to a variety of PCB at relatively low levels (≤0.2 ng/ml), and that concentrations in maternal and cord blood were similar. Concentrations of total PCB (sum or all PCB congeners) averaged more than 2.5 ng/ml, with highest values exceeding 3 ng/ml. Although health implications are uncertain, reports in the literature of PCB-related health effects raise concerns about possible future health consequences, especially obesity and diabetes, in this potentially vulnerable population.

Original languageEnglish (US)
Pages (from-to)1225-1235
Number of pages11
JournalJournal of Toxicology and Environmental Health - Part A: Current Issues
Volume76
Issue number22
DOIs
StatePublished - Nov 17 2013

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

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