TY - JOUR
T1 - Biomarker measurements of prenatal exposure to polychlorinated biphenyls (Pcb) in umbilical cord blood from postpartum hispanic women in Brownsville, Texas
AU - Sexton, Ken
AU - Salinas, Jennifer J.
AU - McDonald, Thomas J.
AU - Gowen, Rose M.Z.
AU - Miller, Rebecca P.
AU - McCormick, Joseph B.
AU - Fisher-Hoch, Susan P.
N1 - Funding Information:
Received 18 June 2013; accepted 23 September 2013. Funding was provided by the University of Texas School of Public Health and the Texas A&M School of Rural Public Health. K. Sexton was partially supported by funds from the National Children’s Study. We thank the women who volunteered to participate in the study and the nurses who helped collect the data. Leticia Armendariz, UT School of Public Health, contributed significantly to the success of the project by coordinating compilation of questionnaire data and collection and shipment of blood specimens. Address correspondence to Ken Sexton, University of Texas School of Public Health, Brownville Regional Campus, 80 Fort Brown– AHC, Brownsville, TX 78520, USA. E-mail: ken.sexton@uth.tmc.edu
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2013/11/17
Y1 - 2013/11/17
N2 - Biomarkers of polychlorinated biphenyls (PCB) were measured in both maternal and umbilical cord blood from 35 pregnant Hispanic women living in Brownsville, TX. Gas chromatography with an electron capture detector (GC/ECD) was used to analyze for 22 PCB analytes. Results indicated that both pregnant mothers and their fetuses were exposed to a variety of PCB at relatively low levels (≤0.2 ng/ml), and that concentrations in maternal and cord blood were similar. Concentrations of total PCB (sum or all PCB congeners) averaged more than 2.5 ng/ml, with highest values exceeding 3 ng/ml. Although health implications are uncertain, reports in the literature of PCB-related health effects raise concerns about possible future health consequences, especially obesity and diabetes, in this potentially vulnerable population.
AB - Biomarkers of polychlorinated biphenyls (PCB) were measured in both maternal and umbilical cord blood from 35 pregnant Hispanic women living in Brownsville, TX. Gas chromatography with an electron capture detector (GC/ECD) was used to analyze for 22 PCB analytes. Results indicated that both pregnant mothers and their fetuses were exposed to a variety of PCB at relatively low levels (≤0.2 ng/ml), and that concentrations in maternal and cord blood were similar. Concentrations of total PCB (sum or all PCB congeners) averaged more than 2.5 ng/ml, with highest values exceeding 3 ng/ml. Although health implications are uncertain, reports in the literature of PCB-related health effects raise concerns about possible future health consequences, especially obesity and diabetes, in this potentially vulnerable population.
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U2 - 10.1080/15287394.2013.848744
DO - 10.1080/15287394.2013.848744
M3 - Article
C2 - 24283394
AN - SCOPUS:84889572993
VL - 76
SP - 1225
EP - 1235
JO - Journal of Toxicology and Environmental Health - Part A: Current Issues
JF - Journal of Toxicology and Environmental Health - Part A: Current Issues
SN - 1528-7394
IS - 22
ER -