Biodegradable poly(α-hydroxy ester) thin films as temporary substrates for retinal pigment epithelium cell transplantation

Robert C. Thomson, Giovanni G. Giordano, Joel H. Collier, Susan L. Ishaug, Antonios G. Mikos, Davjani Lahiri-Munhir, Salima Cumber, Charles A. Garcia

Research output: Contribution to conferencePaperpeer-review

Abstract

A solvent casting technique was developed to produce thin films of four poly(alpha-hydroxy esters) with various thicknesses. These films were characterized with respect to surface morphology, porosity, and flexibility using scanning electron microscope, mercury porosimetry, and dynamic mechanical analysis, respectively. Their suitability as substrates for retinal pigment epithelium (RPE) cells was studied in vitro by assessing human fetal RPE cell attachment, proliferation, and maintenance of differentiated function.

Original languageEnglish (US)
Pages93-94
Number of pages2
StatePublished - 1995
Externally publishedYes
EventProceedings of the 1995 Bioengineering Conference - Beever Creek, CO, USA
Duration: Jun 28 1995Jul 2 1995

Conference

ConferenceProceedings of the 1995 Bioengineering Conference
CityBeever Creek, CO, USA
Period6/28/957/2/95

ASJC Scopus subject areas

  • Engineering(all)

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