Bioassays for itraconazole blood levels: An interlaboratory collaborative study

F. C. Odds; B. Dupont; M. G. Rinaldi; D. A. Stevens; D. W. Warnock; R. Woestenborghs

doi:10.1093/jac/43.5.723

Bioassays for itraconazole blood levels: An interlaboratory collaborative study

F. C. Odds, B. Dupont, M. G. Rinaldi, D. A. Stevens, D. W. Warnock, R. Woestenborghs

Department of Pathology

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Duplicate bioassays for itraconazole and hydroxy-itraconazole were run with 30 serum samples in five laboratories, each using a different method. Both itraconazole and hydroxy-itraconazole were used as standards. Despite quantitative variations, the results of the bioassays correlated sufficiently to indicate the relative level of antifungal activity in the test samples.

Original language	English (US)
Pages (from-to)	723-727
Number of pages	5
Journal	Journal of Antimicrobial Chemotherapy
Volume	43
Issue number	5
DOIs	https://doi.org/10.1093/jac/43.5.723
State	Published - 1999

ASJC Scopus subject areas

Pharmacology
Microbiology (medical)
Infectious Diseases
Pharmacology (medical)

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10.1093/jac/43.5.723

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abstract = "Duplicate bioassays for itraconazole and hydroxy-itraconazole were run with 30 serum samples in five laboratories, each using a different method. Both itraconazole and hydroxy-itraconazole were used as standards. Despite quantitative variations, the results of the bioassays correlated sufficiently to indicate the relative level of antifungal activity in the test samples.",

author = "Odds, {F. C.} and B. Dupont and Rinaldi, {M. G.} and Stevens, {D. A.} and Warnock, {D. W.} and R. Woestenborghs",

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AU - Odds, F. C.

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AU - Stevens, D. A.

AU - Warnock, D. W.

AU - Woestenborghs, R.

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AB - Duplicate bioassays for itraconazole and hydroxy-itraconazole were run with 30 serum samples in five laboratories, each using a different method. Both itraconazole and hydroxy-itraconazole were used as standards. Despite quantitative variations, the results of the bioassays correlated sufficiently to indicate the relative level of antifungal activity in the test samples.

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Bioassays for itraconazole blood levels: An interlaboratory collaborative study

Abstract

ASJC Scopus subject areas

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