Bioassays for itraconazole blood levels: An interlaboratory collaborative study

F. C. Odds, B. Dupont, M. G. Rinaldi, D. A. Stevens, D. W. Warnock, R. Woestenborghs

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Duplicate bioassays for itraconazole and hydroxy-itraconazole were run with 30 serum samples in five laboratories, each using a different method. Both itraconazole and hydroxy-itraconazole were used as standards. Despite quantitative variations, the results of the bioassays correlated sufficiently to indicate the relative level of antifungal activity in the test samples.

Original languageEnglish (US)
Pages (from-to)723-727
Number of pages5
JournalJournal of Antimicrobial Chemotherapy
Volume43
Issue number5
DOIs
StatePublished - 1999

ASJC Scopus subject areas

  • Pharmacology
  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)

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