Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis

J. G. Letourneau, D. L. Day, D. W. Hunter, N. L. Ascher, J. S. Najarian, W. M. Thompson, W. R. Castaneda-Zuniga

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

To determine if biliary complications after liver transplantation are more frequent in patients with preexisting sclerosing cholangitis and to clarify the role of interventional procedures in this setting, the authors reviewed all 40 adult cases in which liver transplantation was performed at their institution over a 3 1/2 -year period. Biliary complications, particularly strictures at the choledochojejunostomy and debris in the intrahepatic and common ducts, were seen in six of ten liver transplant patients (60%) with preexisting sclerosing cholangitis; this is six times the frequency of biliary complications seen in other adult recipients (10%). Biliary complications were definitively diagnosed and managed with interventional radiologic procedures. Obstruction due to anastomotic strictures required treatment with balloon dilation in all six of the affected patients. Obstructive biliary complications occur in many liver recipients with preexisting sclerosing cholangitis. These complications require aggressive radiologic assessment and intervention but to date have not adversely affected survival.

Original languageEnglish (US)
Pages (from-to)349-351
Number of pages3
JournalRadiology
Volume167
Issue number2
StatePublished - 1988
Externally publishedYes

Fingerprint

Sclerosing Cholangitis
Liver Transplantation
Pathologic Constriction
Choledochostomy
Liver
Dilatation
Transplants
Survival
Therapeutics

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Letourneau, J. G., Day, D. L., Hunter, D. W., Ascher, N. L., Najarian, J. S., Thompson, W. M., & Castaneda-Zuniga, W. R. (1988). Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis. Radiology, 167(2), 349-351.

Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis. / Letourneau, J. G.; Day, D. L.; Hunter, D. W.; Ascher, N. L.; Najarian, J. S.; Thompson, W. M.; Castaneda-Zuniga, W. R.

In: Radiology, Vol. 167, No. 2, 1988, p. 349-351.

Research output: Contribution to journalArticle

Letourneau, JG, Day, DL, Hunter, DW, Ascher, NL, Najarian, JS, Thompson, WM & Castaneda-Zuniga, WR 1988, 'Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis', Radiology, vol. 167, no. 2, pp. 349-351.
Letourneau JG, Day DL, Hunter DW, Ascher NL, Najarian JS, Thompson WM et al. Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis. Radiology. 1988;167(2):349-351.
Letourneau, J. G. ; Day, D. L. ; Hunter, D. W. ; Ascher, N. L. ; Najarian, J. S. ; Thompson, W. M. ; Castaneda-Zuniga, W. R. / Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis. In: Radiology. 1988 ; Vol. 167, No. 2. pp. 349-351.
@article{386abad88271437c83a93b1767f34464,
title = "Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis",
abstract = "To determine if biliary complications after liver transplantation are more frequent in patients with preexisting sclerosing cholangitis and to clarify the role of interventional procedures in this setting, the authors reviewed all 40 adult cases in which liver transplantation was performed at their institution over a 3 1/2 -year period. Biliary complications, particularly strictures at the choledochojejunostomy and debris in the intrahepatic and common ducts, were seen in six of ten liver transplant patients (60{\%}) with preexisting sclerosing cholangitis; this is six times the frequency of biliary complications seen in other adult recipients (10{\%}). Biliary complications were definitively diagnosed and managed with interventional radiologic procedures. Obstruction due to anastomotic strictures required treatment with balloon dilation in all six of the affected patients. Obstructive biliary complications occur in many liver recipients with preexisting sclerosing cholangitis. These complications require aggressive radiologic assessment and intervention but to date have not adversely affected survival.",
author = "Letourneau, {J. G.} and Day, {D. L.} and Hunter, {D. W.} and Ascher, {N. L.} and Najarian, {J. S.} and Thompson, {W. M.} and Castaneda-Zuniga, {W. R.}",
year = "1988",
language = "English (US)",
volume = "167",
pages = "349--351",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "2",

}

TY - JOUR

T1 - Biliary complications after liver transplantation in patients with preexisting sclerosing cholangitis

AU - Letourneau, J. G.

AU - Day, D. L.

AU - Hunter, D. W.

AU - Ascher, N. L.

AU - Najarian, J. S.

AU - Thompson, W. M.

AU - Castaneda-Zuniga, W. R.

PY - 1988

Y1 - 1988

N2 - To determine if biliary complications after liver transplantation are more frequent in patients with preexisting sclerosing cholangitis and to clarify the role of interventional procedures in this setting, the authors reviewed all 40 adult cases in which liver transplantation was performed at their institution over a 3 1/2 -year period. Biliary complications, particularly strictures at the choledochojejunostomy and debris in the intrahepatic and common ducts, were seen in six of ten liver transplant patients (60%) with preexisting sclerosing cholangitis; this is six times the frequency of biliary complications seen in other adult recipients (10%). Biliary complications were definitively diagnosed and managed with interventional radiologic procedures. Obstruction due to anastomotic strictures required treatment with balloon dilation in all six of the affected patients. Obstructive biliary complications occur in many liver recipients with preexisting sclerosing cholangitis. These complications require aggressive radiologic assessment and intervention but to date have not adversely affected survival.

AB - To determine if biliary complications after liver transplantation are more frequent in patients with preexisting sclerosing cholangitis and to clarify the role of interventional procedures in this setting, the authors reviewed all 40 adult cases in which liver transplantation was performed at their institution over a 3 1/2 -year period. Biliary complications, particularly strictures at the choledochojejunostomy and debris in the intrahepatic and common ducts, were seen in six of ten liver transplant patients (60%) with preexisting sclerosing cholangitis; this is six times the frequency of biliary complications seen in other adult recipients (10%). Biliary complications were definitively diagnosed and managed with interventional radiologic procedures. Obstruction due to anastomotic strictures required treatment with balloon dilation in all six of the affected patients. Obstructive biliary complications occur in many liver recipients with preexisting sclerosing cholangitis. These complications require aggressive radiologic assessment and intervention but to date have not adversely affected survival.

UR - http://www.scopus.com/inward/record.url?scp=0023908682&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023908682&partnerID=8YFLogxK

M3 - Article

C2 - 3282255

AN - SCOPUS:0023908682

VL - 167

SP - 349

EP - 351

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 2

ER -