Bi-allelic amplification of ATM gene in blastoid variant of mantle cell lymphoma: a novel mechanism of inactivation due to chromoanagenesis?

Medicine and Dentistry

• Mantle Cell Lymphoma 100%
• Gene 100%
• Microarray 40%
• Heterozygosity 40%
• Cells 40%
• Bone Marrow 40%
• Neoplasm 20%
• Protein P53 20%
• Diagnosis 20%
• Lymphadenopathy 20%
• Chromosome 11 20%
• Lymphocytic Infiltration 20%
• Dyspnea 20%
• Chromosome 7 20%
• Karyotype 20%
• Chromosome Analysis 20%
• Splenomegaly 20%
• B-Cell Lymphoma 20%
• Chill 20%
• B Cell 20%
• Leukocytosis 20%
• Case Presentation 20%
• Gene Amplification 20%
• Fever 20%
• Analysis 20%
• Male 20%
• Patient 20%
• Biopsy 20%
• Mutant 20%
• Prognosis 20%
• Blood 20%

Biochemistry, Genetics and Molecular Biology

• Nested Gene 100%
• B Cell 66%
• Loss of Heterozygosity 66%
• Bone 66%
• Microarray 66%
• Chromosome 33%
• Allele 33%
• P53 33%
• Karyotype 33%
• Cytogenetics 33%
• Chromosome 11 33%
• Gene Amplification 33%
• Chromosome 7 33%
• CD5 33%
• Single Nucleotide Polymorphism 33%
• Mutant 33%