Benign prostatic hypertrophy: Retrograde transurethral dilation of the prostatic urethra in humans

F. Castaneda, P. Reddy, N. Wasserman, J. Hulbert, G. Lund, J. G. Letourneau, D. W. Hunter, W. R. Castaneda-Zuniga, K. Amplatz

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Retrograde transurethral balloon dilation of the prostatic urethra was performed in five human volunteers with benign prostatic hypertrophy. Each patient underwent cystoscopy, uroflow studies, voiding cystourethrography, retrograde urethrography, and magnetic resonance imaging before dilation and at defined intervals afterward. The longest follow-up to date is 8 months. Patients were given topical anesthetics and mild sedatives, and dilation was performed with a 25-mm urethroplasty balloon catheter inflated at 3-6 atm for 10 minutes. All catheter manipulations were done with a guide wire and under fluoroscopic control. Significant resolution of symptoms of prostatism was seen in four patients. The unsatisfactory results in the last patient were believed to be caused by ineffectual dilation of predominantly middle lobe hypertrophy - a condition that is now regarded as a contraindication to dilation. This technique has promise to replace transurethral resection of the prostate as the treatment of choice for this common male ailment.

Original languageEnglish (US)
Pages (from-to)649-654
Number of pages6
JournalRadiology
Volume163
Issue number3
StatePublished - Aug 4 1987

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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