Bedside assessment of frontal degeneration: Distinguishing Alzheimer's disease from non-Alzheimer's cortical dementia

Donald R Royall, R. K. Mahurin, J. Cornell

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Two instruments, the Executive Interview (EXIT) and the Qualitative Evaluation of Dementia (QED), that are useful in the evaluation of frontal system failure are discussed. The ability of these instruments to discriminate frontal-type dementia (FTD) from Alzheimer's disease (AD) and the dementia of major depression (DMD) was examined in 100 consecutive elderly dementia patients presenting to a multidisciplinary geriatric clinic. All groups showed executive impairment by the EXIT, and 46% of the FTD patients were found to be unimpaired by the Mini-Mental State Examination (MMSE). The AD and FTD groups differed significantly from the DMD group on the QED. The QED alone could not distinguish AD from FTD cases. However, mapping of EXIT scores against MMSE (errors) scores revealed that AD and FTD follow very different regression lines.

Original languageEnglish (US)
Pages (from-to)95-103
Number of pages9
JournalExperimental Aging Research
Volume20
Issue number2
StatePublished - 1994

Fingerprint

Dementia
Alzheimer Disease
Interviews
Alzheimer's Disease
Degeneration
Depression
Aptitude
Geriatrics
Evaluation

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology
  • Psychology(all)

Cite this

Bedside assessment of frontal degeneration : Distinguishing Alzheimer's disease from non-Alzheimer's cortical dementia. / Royall, Donald R; Mahurin, R. K.; Cornell, J.

In: Experimental Aging Research, Vol. 20, No. 2, 1994, p. 95-103.

Research output: Contribution to journalArticle

@article{a63ab7a5c81544249ae3167a1928d306,
title = "Bedside assessment of frontal degeneration: Distinguishing Alzheimer's disease from non-Alzheimer's cortical dementia",
abstract = "Two instruments, the Executive Interview (EXIT) and the Qualitative Evaluation of Dementia (QED), that are useful in the evaluation of frontal system failure are discussed. The ability of these instruments to discriminate frontal-type dementia (FTD) from Alzheimer's disease (AD) and the dementia of major depression (DMD) was examined in 100 consecutive elderly dementia patients presenting to a multidisciplinary geriatric clinic. All groups showed executive impairment by the EXIT, and 46{\%} of the FTD patients were found to be unimpaired by the Mini-Mental State Examination (MMSE). The AD and FTD groups differed significantly from the DMD group on the QED. The QED alone could not distinguish AD from FTD cases. However, mapping of EXIT scores against MMSE (errors) scores revealed that AD and FTD follow very different regression lines.",
author = "Royall, {Donald R} and Mahurin, {R. K.} and J. Cornell",
year = "1994",
language = "English (US)",
volume = "20",
pages = "95--103",
journal = "Experimental Aging Research",
issn = "0361-073X",
publisher = "Taylor and Francis Ltd.",
number = "2",

}

TY - JOUR

T1 - Bedside assessment of frontal degeneration

T2 - Distinguishing Alzheimer's disease from non-Alzheimer's cortical dementia

AU - Royall, Donald R

AU - Mahurin, R. K.

AU - Cornell, J.

PY - 1994

Y1 - 1994

N2 - Two instruments, the Executive Interview (EXIT) and the Qualitative Evaluation of Dementia (QED), that are useful in the evaluation of frontal system failure are discussed. The ability of these instruments to discriminate frontal-type dementia (FTD) from Alzheimer's disease (AD) and the dementia of major depression (DMD) was examined in 100 consecutive elderly dementia patients presenting to a multidisciplinary geriatric clinic. All groups showed executive impairment by the EXIT, and 46% of the FTD patients were found to be unimpaired by the Mini-Mental State Examination (MMSE). The AD and FTD groups differed significantly from the DMD group on the QED. The QED alone could not distinguish AD from FTD cases. However, mapping of EXIT scores against MMSE (errors) scores revealed that AD and FTD follow very different regression lines.

AB - Two instruments, the Executive Interview (EXIT) and the Qualitative Evaluation of Dementia (QED), that are useful in the evaluation of frontal system failure are discussed. The ability of these instruments to discriminate frontal-type dementia (FTD) from Alzheimer's disease (AD) and the dementia of major depression (DMD) was examined in 100 consecutive elderly dementia patients presenting to a multidisciplinary geriatric clinic. All groups showed executive impairment by the EXIT, and 46% of the FTD patients were found to be unimpaired by the Mini-Mental State Examination (MMSE). The AD and FTD groups differed significantly from the DMD group on the QED. The QED alone could not distinguish AD from FTD cases. However, mapping of EXIT scores against MMSE (errors) scores revealed that AD and FTD follow very different regression lines.

UR - http://www.scopus.com/inward/record.url?scp=0028206625&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028206625&partnerID=8YFLogxK

M3 - Article

C2 - 8020544

AN - SCOPUS:0028206625

VL - 20

SP - 95

EP - 103

JO - Experimental Aging Research

JF - Experimental Aging Research

SN - 0361-073X

IS - 2

ER -