Basic science of articular cartilage repair

Kyriacos A. Athanasiou; Amita R. Shah; R. Jason Hernandez; Richard G. LeBaron

doi:10.1016/S0278-5919(05)70304-5

Basic science of articular cartilage repair

Kyriacos A. Athanasiou, Amita R. Shah, R. Jason Hernandez, Richard G. LeBaron

Research output: Contribution to journal › Article › peer-review

101 Scopus citations

Abstract

Much is still unknown related to the basic science of articular cartilage healing. This article discusses some of theses issues and also experimental studies attempting to enhance cartilage regeneration. Special emphasis is placed on new methods used for the synthesis of articular cartilage ex vivo, in conjunction with bioreactors, which are used to modulate the mechanical environment of cell seeded scaffolds. Also promising are efforts related to the design and use of biodegradable scaffolds that can be used to tissue engineer articular cartilage. The author's thoughts on potential future improvements are also presented.

Original language	English (US)
Pages (from-to)	223-247
Number of pages	25
Journal	Clinics in sports medicine
Volume	20
Issue number	2
DOIs	https://doi.org/10.1016/S0278-5919(05)70304-5
State	Published - 2001
Externally published	Yes

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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10.1016/S0278-5919(05)70304-5

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AB - Much is still unknown related to the basic science of articular cartilage healing. This article discusses some of theses issues and also experimental studies attempting to enhance cartilage regeneration. Special emphasis is placed on new methods used for the synthesis of articular cartilage ex vivo, in conjunction with bioreactors, which are used to modulate the mechanical environment of cell seeded scaffolds. Also promising are efforts related to the design and use of biodegradable scaffolds that can be used to tissue engineer articular cartilage. The author's thoughts on potential future improvements are also presented.

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Basic science of articular cartilage repair

Abstract

ASJC Scopus subject areas

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