Basic principles and neurosurgical applications of positron emission tomography

J. Xiong, L. D H Nickerson, J. H. Downs, Peter T Fox

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The importance clinical applications of PET in neurosurgery include localization of epileptic foci, diagnosis of brain tumors, preoperative brain mapping, and the study of plasticity of brain following brain damage: Conclusions are summarized as follows: PET can noninvasively localize the epileptogenic focus in patients with partial epilepsy and can detect the epileptogenicity that is undetectable by structural imaging methods, such as MR imaging and CT PET provides the ability to investigate the physiology of primary and metastatic intracranial tumors and to examine tumor physiological variables, such as glucose metabolism, blood flow, amino acid uptake, protein synthesis, and cell proliferation rate PET can provide highly precise maps of brain function. With lower risk, lower cost, and higher accuracy, PET offers an alternative to the invasive Wada test PET can be used to investigate plasticity of the brain in patients with brain damage.

Original languageEnglish (US)
Pages (from-to)293-306
Number of pages14
JournalNeurosurgery Clinics of North America
Volume8
Issue number3
StatePublished - 1997

Fingerprint

Positron-Emission Tomography
Brain
Brain Mapping
Partial Epilepsy
Neurosurgery
Brain Neoplasms
Blood Glucose
Neoplasms
Cell Proliferation
Amino Acids
Costs and Cost Analysis
Proteins

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Basic principles and neurosurgical applications of positron emission tomography. / Xiong, J.; Nickerson, L. D H; Downs, J. H.; Fox, Peter T.

In: Neurosurgery Clinics of North America, Vol. 8, No. 3, 1997, p. 293-306.

Research output: Contribution to journalArticle

Xiong, J. ; Nickerson, L. D H ; Downs, J. H. ; Fox, Peter T. / Basic principles and neurosurgical applications of positron emission tomography. In: Neurosurgery Clinics of North America. 1997 ; Vol. 8, No. 3. pp. 293-306.
@article{d7e93fcf22a645808daaa095adf63588,
title = "Basic principles and neurosurgical applications of positron emission tomography",
abstract = "The importance clinical applications of PET in neurosurgery include localization of epileptic foci, diagnosis of brain tumors, preoperative brain mapping, and the study of plasticity of brain following brain damage: Conclusions are summarized as follows: PET can noninvasively localize the epileptogenic focus in patients with partial epilepsy and can detect the epileptogenicity that is undetectable by structural imaging methods, such as MR imaging and CT PET provides the ability to investigate the physiology of primary and metastatic intracranial tumors and to examine tumor physiological variables, such as glucose metabolism, blood flow, amino acid uptake, protein synthesis, and cell proliferation rate PET can provide highly precise maps of brain function. With lower risk, lower cost, and higher accuracy, PET offers an alternative to the invasive Wada test PET can be used to investigate plasticity of the brain in patients with brain damage.",
author = "J. Xiong and Nickerson, {L. D H} and Downs, {J. H.} and Fox, {Peter T}",
year = "1997",
language = "English (US)",
volume = "8",
pages = "293--306",
journal = "Neurosurgery Clinics of North America",
issn = "1042-3680",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - Basic principles and neurosurgical applications of positron emission tomography

AU - Xiong, J.

AU - Nickerson, L. D H

AU - Downs, J. H.

AU - Fox, Peter T

PY - 1997

Y1 - 1997

N2 - The importance clinical applications of PET in neurosurgery include localization of epileptic foci, diagnosis of brain tumors, preoperative brain mapping, and the study of plasticity of brain following brain damage: Conclusions are summarized as follows: PET can noninvasively localize the epileptogenic focus in patients with partial epilepsy and can detect the epileptogenicity that is undetectable by structural imaging methods, such as MR imaging and CT PET provides the ability to investigate the physiology of primary and metastatic intracranial tumors and to examine tumor physiological variables, such as glucose metabolism, blood flow, amino acid uptake, protein synthesis, and cell proliferation rate PET can provide highly precise maps of brain function. With lower risk, lower cost, and higher accuracy, PET offers an alternative to the invasive Wada test PET can be used to investigate plasticity of the brain in patients with brain damage.

AB - The importance clinical applications of PET in neurosurgery include localization of epileptic foci, diagnosis of brain tumors, preoperative brain mapping, and the study of plasticity of brain following brain damage: Conclusions are summarized as follows: PET can noninvasively localize the epileptogenic focus in patients with partial epilepsy and can detect the epileptogenicity that is undetectable by structural imaging methods, such as MR imaging and CT PET provides the ability to investigate the physiology of primary and metastatic intracranial tumors and to examine tumor physiological variables, such as glucose metabolism, blood flow, amino acid uptake, protein synthesis, and cell proliferation rate PET can provide highly precise maps of brain function. With lower risk, lower cost, and higher accuracy, PET offers an alternative to the invasive Wada test PET can be used to investigate plasticity of the brain in patients with brain damage.

UR - http://www.scopus.com/inward/record.url?scp=0030861743&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030861743&partnerID=8YFLogxK

M3 - Article

C2 - 9188539

AN - SCOPUS:0030861743

VL - 8

SP - 293

EP - 306

JO - Neurosurgery Clinics of North America

JF - Neurosurgery Clinics of North America

SN - 1042-3680

IS - 3

ER -