Baboon as a nonhuman primate model for vaccine studies

Krishna K. Murthy, Mary T. Salas, Kenneth D. Carey, Jean L. Patterson

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations

    Abstract

    Nonhuman primates are suitable and valid models to determine the safety, immunogenicity and efficacy of candidate vaccines that are being developed for human application. Among the nonhuman primates, baboons have been found to be ideal for vaccine studies because they are phylogenetically closer to humans, have a similar immune system and response and are available in large numbers. During the last two decades, numerous candidate vaccines have been evaluated in the baboon model.

    Original languageEnglish (US)
    Pages (from-to)4622-4624
    Number of pages3
    JournalVaccine
    Volume24
    Issue number21
    DOIs
    StatePublished - May 22 2006

    Keywords

    • Baboons
    • Candidate vaccines
    • Immunogenicity
    • Nonhuman primates

    ASJC Scopus subject areas

    • Molecular Medicine
    • Immunology and Microbiology(all)
    • veterinary(all)
    • Public Health, Environmental and Occupational Health
    • Infectious Diseases

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