Baboon as a nonhuman primate model for vaccine studies

Krishna K. Murthy; Mary T. Salas; Kenneth D. Carey; Jean L. Patterson

doi:10.1016/j.vaccine.2005.08.047

Baboon as a nonhuman primate model for vaccine studies

Krishna K. Murthy, Mary T. Salas, Kenneth D. Carey, Jean L. Patterson

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Nonhuman primates are suitable and valid models to determine the safety, immunogenicity and efficacy of candidate vaccines that are being developed for human application. Among the nonhuman primates, baboons have been found to be ideal for vaccine studies because they are phylogenetically closer to humans, have a similar immune system and response and are available in large numbers. During the last two decades, numerous candidate vaccines have been evaluated in the baboon model.

Original language	English (US)
Pages (from-to)	4622-4624
Number of pages	3
Journal	Vaccine
Volume	24
Issue number	21
DOIs	https://doi.org/10.1016/j.vaccine.2005.08.047
State	Published - May 22 2006

Keywords

Baboons
Candidate vaccines
Immunogenicity
Nonhuman primates

ASJC Scopus subject areas

Molecular Medicine
Immunology and Microbiology(all)
veterinary(all)
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1016/j.vaccine.2005.08.047

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AU - Carey, Kenneth D.

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Baboon as a nonhuman primate model for vaccine studies

Abstract

Keywords

ASJC Scopus subject areas

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