Baboon as a nonhuman primate model for vaccine studies

Krishna K. Murthy, Mary T. Salas, Kenneth D. Carey, Jean L. Patterson

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations


    Nonhuman primates are suitable and valid models to determine the safety, immunogenicity and efficacy of candidate vaccines that are being developed for human application. Among the nonhuman primates, baboons have been found to be ideal for vaccine studies because they are phylogenetically closer to humans, have a similar immune system and response and are available in large numbers. During the last two decades, numerous candidate vaccines have been evaluated in the baboon model.

    Original languageEnglish (US)
    Pages (from-to)4622-4624
    Number of pages3
    Issue number21
    StatePublished - May 22 2006


    • Baboons
    • Candidate vaccines
    • Immunogenicity
    • Nonhuman primates

    ASJC Scopus subject areas

    • Molecular Medicine
    • Immunology and Microbiology(all)
    • veterinary(all)
    • Public Health, Environmental and Occupational Health
    • Infectious Diseases


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