Autofluorescence of normal and malignant bronchial tissue

Jaclyn Hung, Stephen Lam, Jean C. Leriche, Branko Palcic

Research output: Contribution to journalArticle

353 Scopus citations

Abstract

In vivo autofluorescence spectra were obtained in 5 patients with carcinoma in situ, 26 patients with invasive tumors, and 1 patient with severe dysplasia. Significant spectral differences were observed between pre‐cancerous, cancerous, and normal bronchial tissues. This difference may afford a method to image and/or detect early lung cancer by using tissue autofluorescence alone.

Original languageEnglish (US)
Pages (from-to)99-105
Number of pages7
JournalLasers in Surgery and Medicine
Volume11
Issue number2
DOIs
StatePublished - 1991

Keywords

  • bronchial tissue
  • carcinoma in situ
  • in vivo autofluorescence
  • lasers
  • severe dysplasia

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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