Autofluorescence of normal and malignant bronchial tissue

Jaclyn Hung; Stephen Lam; Jean C. Leriche; Branko Palcic

doi:10.1002/lsm.1900110203

Autofluorescence of normal and malignant bronchial tissue

Jaclyn Hung, Stephen Lam, Jean C. Leriche, Branko Palcic

Pediatrics

Research output: Contribution to journal › Article › peer-review

357 Scopus citations

Abstract

In vivo autofluorescence spectra were obtained in 5 patients with carcinoma in situ, 26 patients with invasive tumors, and 1 patient with severe dysplasia. Significant spectral differences were observed between pre‐cancerous, cancerous, and normal bronchial tissues. This difference may afford a method to image and/or detect early lung cancer by using tissue autofluorescence alone.

Original language	English (US)
Pages (from-to)	99-105
Number of pages	7
Journal	Lasers in Surgery and Medicine
Volume	11
Issue number	2
DOIs	https://doi.org/10.1002/lsm.1900110203
State	Published - 1991

Keywords

bronchial tissue
carcinoma in situ
in vivo autofluorescence
lasers
severe dysplasia

ASJC Scopus subject areas

Surgery
Dermatology

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10.1002/lsm.1900110203

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title = "Autofluorescence of normal and malignant bronchial tissue",

abstract = "In vivo autofluorescence spectra were obtained in 5 patients with carcinoma in situ, 26 patients with invasive tumors, and 1 patient with severe dysplasia. Significant spectral differences were observed between pre‐cancerous, cancerous, and normal bronchial tissues. This difference may afford a method to image and/or detect early lung cancer by using tissue autofluorescence alone.",

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author = "Jaclyn Hung and Stephen Lam and Leriche, {Jean C.} and Branko Palcic",

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KW - carcinoma in situ

KW - in vivo autofluorescence

KW - lasers

KW - severe dysplasia

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