TY - JOUR
T1 - Atypical MRI features involving the brain in Wilson's disease
AU - Yousaf, Muhammad
AU - Kumar, Manoj
AU - Ramakrishnaiah, Raghu
AU - Vanhemert, Rudy
AU - Angtuaco, Edgardo
N1 - Publisher Copyright:
© 2009 The Authors.
PY - 2009
Y1 - 2009
N2 - Wilson's disease is an inborn error of copper metabolism characterized by inability of the liver to excrete copper into the bile, with excessive deposition of copper primarily in the liver and in the brain. The lentiform nuclei are involved, most often followed by involvement of the thalami, the pons, midbrain, superior and inferior cerebellar peduncles, and the cerebellar nuclei. Predominant involvement of the thalami and brainstem with no significant involvement of the lentiform nuclei is not common. We present a case of Wilson's disease with minimal involvement of the lentiform nuclei, with marked lesions involving the thalami, midbrain, and pons.
AB - Wilson's disease is an inborn error of copper metabolism characterized by inability of the liver to excrete copper into the bile, with excessive deposition of copper primarily in the liver and in the brain. The lentiform nuclei are involved, most often followed by involvement of the thalami, the pons, midbrain, superior and inferior cerebellar peduncles, and the cerebellar nuclei. Predominant involvement of the thalami and brainstem with no significant involvement of the lentiform nuclei is not common. We present a case of Wilson's disease with minimal involvement of the lentiform nuclei, with marked lesions involving the thalami, midbrain, and pons.
UR - https://www.scopus.com/pages/publications/84964355703
UR - https://www.scopus.com/pages/publications/84964355703#tab=citedBy
U2 - 10.2484/rcr.v4i3.312
DO - 10.2484/rcr.v4i3.312
M3 - Article
AN - SCOPUS:84964355703
SN - 1930-0433
VL - 4
SP - 312
JO - Radiology Case Reports
JF - Radiology Case Reports
IS - 3
M1 - 312
ER -