Atypical MRI features involving the brain in Wilson's disease

Muhammad Yousaf, Manoj Kumar, Raghu Ramakrishnaiah, Rudy Vanhemert, Edgardo Angtuaco

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Wilson's disease is an inborn error of copper metabolism characterized by inability of the liver to excrete copper into the bile, with excessive deposition of copper primarily in the liver and in the brain. The lentiform nuclei are involved, most often followed by involvement of the thalami, the pons, midbrain, superior and inferior cerebellar peduncles, and the cerebellar nuclei. Predominant involvement of the thalami and brainstem with no significant involvement of the lentiform nuclei is not common. We present a case of Wilson's disease with minimal involvement of the lentiform nuclei, with marked lesions involving the thalami, midbrain, and pons.

Original languageEnglish (US)
Article number312
Pages (from-to)312
Number of pages1
JournalRadiology Case Reports
Issue number3
StatePublished - 2009
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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