Attention-deficit hyperactivity symptomatology after traumatic brain injury: A prospective study

Jeffrey E. Max; Stephan Arndt; Carlos S. Castillo; Hirokazu Bokura; Donald A. Robin; Scott D. Lindgren; Wilbur L. Smith; Yutaka Sato; Philip J. Mattheis

doi:10.1097/00004583-199808000-00014

Attention-deficit hyperactivity symptomatology after traumatic brain injury: A prospective study

Jeffrey E. Max, Stephan Arndt, Carlos S. Castillo, Hirokazu Bokura, Donald A. Robin, Scott D. Lindgren, Wilbur L. Smith, Yutaka Sato, Philip J. Mattheis

Research Imaging Institute

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

Abstract

Objective: To study prospectively the course of attention-deficit hyperactivity (ADH) symptomatology in children and adolescents after traumatic brain injury (TBI). It was hypothesized that ADH symptomatology would be significantly related to severity of injury. Method: Subjects were children (n = 50) aged 6 to 14 years at the time they were hospitalized after TBI. The study used a prospective follow-up design. Assessments of preinjury psychiatric, behavioral, socioeconomic, family functioning, and family psychiatric history status were conducted. Severity of injury was assessed by standard clinical scales, and neuroimaging was analyzed. Results: The main finding of this study was that change in ADH symptomatology in the first 2 years after TBI in children and adolescents was significantly related to severity of injury. Overall ADH symptomatology during the study was significantly related to a measure of family dysfunction when family psychiatric history, socioeconomic status, and severity of injury were controlled. Conclusion: The presence of a positive 'dose-response' relationship between severity of injury and change in ADH symptoms, present from the 3-month assessment, was consistent with an effect directly related to brain damage.

Original language	English (US)
Pages (from-to)	841-847
Number of pages	7
Journal	Journal of the American Academy of Child and Adolescent Psychiatry
Volume	37
Issue number	8
DOIs	https://doi.org/10.1097/00004583-199808000-00014
State	Published - Aug 1998

Keywords

Attention-deficit hyperactivity disorder
Traumatic brain injury

ASJC Scopus subject areas

Developmental and Educational Psychology
Psychiatry and Mental health

Access to Document

10.1097/00004583-199808000-00014

Fingerprint Dive into the research topics of 'Attention-deficit hyperactivity symptomatology after traumatic brain injury: A prospective study'. Together they form a unique fingerprint.

Cite this

Attention-deficit hyperactivity symptomatology after traumatic brain injury : A prospective study. / Max, Jeffrey E.; Arndt, Stephan; Castillo, Carlos S.; Bokura, Hirokazu; Robin, Donald A.; Lindgren, Scott D.; Smith, Wilbur L.; Sato, Yutaka; Mattheis, Philip J.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 37, No. 8, 08.1998, p. 841-847.

Research output: Contribution to journal › Article › peer-review

Max, Jeffrey E. ; Arndt, Stephan ; Castillo, Carlos S. ; Bokura, Hirokazu ; Robin, Donald A. ; Lindgren, Scott D. ; Smith, Wilbur L. ; Sato, Yutaka ; Mattheis, Philip J. / Attention-deficit hyperactivity symptomatology after traumatic brain injury : A prospective study. In: Journal of the American Academy of Child and Adolescent Psychiatry. 1998 ; Vol. 37, No. 8. pp. 841-847.

@article{5b8df9df38754e87a462ed9dabd61d09,

title = "Attention-deficit hyperactivity symptomatology after traumatic brain injury: A prospective study",

abstract = "Objective: To study prospectively the course of attention-deficit hyperactivity (ADH) symptomatology in children and adolescents after traumatic brain injury (TBI). It was hypothesized that ADH symptomatology would be significantly related to severity of injury. Method: Subjects were children (n = 50) aged 6 to 14 years at the time they were hospitalized after TBI. The study used a prospective follow-up design. Assessments of preinjury psychiatric, behavioral, socioeconomic, family functioning, and family psychiatric history status were conducted. Severity of injury was assessed by standard clinical scales, and neuroimaging was analyzed. Results: The main finding of this study was that change in ADH symptomatology in the first 2 years after TBI in children and adolescents was significantly related to severity of injury. Overall ADH symptomatology during the study was significantly related to a measure of family dysfunction when family psychiatric history, socioeconomic status, and severity of injury were controlled. Conclusion: The presence of a positive 'dose-response' relationship between severity of injury and change in ADH symptoms, present from the 3-month assessment, was consistent with an effect directly related to brain damage.",

keywords = "Attention-deficit hyperactivity disorder, Traumatic brain injury",

author = "Max, {Jeffrey E.} and Stephan Arndt and Castillo, {Carlos S.} and Hirokazu Bokura and Robin, {Donald A.} and Lindgren, {Scott D.} and Smith, {Wilbur L.} and Yutaka Sato and Mattheis, {Philip J.}",

note = "Funding Information: Accepted March 3, 1938. From the Departments of Psychiaty (Drs. Max and Arndt), Radiology (Drs. Smith and Sato), Pediatrics (Dr. Lindgren), and Speech Pathology and Audiology (Dr. Robin), University of Iowa, Iowa City; Yasugi Daiichi Hospital, Shimane, Japan (Dr. Bokura); Universityo fMontana, Missoula (Dr. Mattheis); and Cedar Centre Psychiatric Group, Cedar Uapids, L4 (Dr. Castillo). This research was supported by a NARSAD Young Investigator Award (Dr. Max) and NIMH grants MH31593, MH40856, and MHCRC43271 (Dr. Arndt). The authors acknowledge the helpfir1 comments of Robert Robinson, M.D., and May Morrisey, B.A., Paq Shannon, B.A., and Erika Gaylor, B.S., fir collection of some of the data. Reprint requests to Dr. Mm, Department of Pychiaty, University of Iowa, 1876 JPt Iowa City, 1A 52242.",

year = "1998",

month = aug,

doi = "10.1097/00004583-199808000-00014",

language = "English (US)",

volume = "37",

pages = "841--847",

journal = "Journal of the American Academy of Child and Adolescent Psychiatry",

issn = "0890-8567",

publisher = "Elsevier Limited",

number = "8",

}

TY - JOUR

T1 - Attention-deficit hyperactivity symptomatology after traumatic brain injury

T2 - A prospective study

AU - Max, Jeffrey E.

AU - Arndt, Stephan

AU - Castillo, Carlos S.

AU - Bokura, Hirokazu

AU - Robin, Donald A.

AU - Lindgren, Scott D.

AU - Smith, Wilbur L.

AU - Sato, Yutaka

AU - Mattheis, Philip J.

N1 - Funding Information: Accepted March 3, 1938. From the Departments of Psychiaty (Drs. Max and Arndt), Radiology (Drs. Smith and Sato), Pediatrics (Dr. Lindgren), and Speech Pathology and Audiology (Dr. Robin), University of Iowa, Iowa City; Yasugi Daiichi Hospital, Shimane, Japan (Dr. Bokura); Universityo fMontana, Missoula (Dr. Mattheis); and Cedar Centre Psychiatric Group, Cedar Uapids, L4 (Dr. Castillo). This research was supported by a NARSAD Young Investigator Award (Dr. Max) and NIMH grants MH31593, MH40856, and MHCRC43271 (Dr. Arndt). The authors acknowledge the helpfir1 comments of Robert Robinson, M.D., and May Morrisey, B.A., Paq Shannon, B.A., and Erika Gaylor, B.S., fir collection of some of the data. Reprint requests to Dr. Mm, Department of Pychiaty, University of Iowa, 1876 JPt Iowa City, 1A 52242.

PY - 1998/8

Y1 - 1998/8

N2 - Objective: To study prospectively the course of attention-deficit hyperactivity (ADH) symptomatology in children and adolescents after traumatic brain injury (TBI). It was hypothesized that ADH symptomatology would be significantly related to severity of injury. Method: Subjects were children (n = 50) aged 6 to 14 years at the time they were hospitalized after TBI. The study used a prospective follow-up design. Assessments of preinjury psychiatric, behavioral, socioeconomic, family functioning, and family psychiatric history status were conducted. Severity of injury was assessed by standard clinical scales, and neuroimaging was analyzed. Results: The main finding of this study was that change in ADH symptomatology in the first 2 years after TBI in children and adolescents was significantly related to severity of injury. Overall ADH symptomatology during the study was significantly related to a measure of family dysfunction when family psychiatric history, socioeconomic status, and severity of injury were controlled. Conclusion: The presence of a positive 'dose-response' relationship between severity of injury and change in ADH symptoms, present from the 3-month assessment, was consistent with an effect directly related to brain damage.

AB - Objective: To study prospectively the course of attention-deficit hyperactivity (ADH) symptomatology in children and adolescents after traumatic brain injury (TBI). It was hypothesized that ADH symptomatology would be significantly related to severity of injury. Method: Subjects were children (n = 50) aged 6 to 14 years at the time they were hospitalized after TBI. The study used a prospective follow-up design. Assessments of preinjury psychiatric, behavioral, socioeconomic, family functioning, and family psychiatric history status were conducted. Severity of injury was assessed by standard clinical scales, and neuroimaging was analyzed. Results: The main finding of this study was that change in ADH symptomatology in the first 2 years after TBI in children and adolescents was significantly related to severity of injury. Overall ADH symptomatology during the study was significantly related to a measure of family dysfunction when family psychiatric history, socioeconomic status, and severity of injury were controlled. Conclusion: The presence of a positive 'dose-response' relationship between severity of injury and change in ADH symptoms, present from the 3-month assessment, was consistent with an effect directly related to brain damage.

KW - Attention-deficit hyperactivity disorder

KW - Traumatic brain injury

UR - http://www.scopus.com/inward/record.url?scp=0031879369&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031879369&partnerID=8YFLogxK

U2 - 10.1097/00004583-199808000-00014

DO - 10.1097/00004583-199808000-00014

M3 - Article

C2 - 9695446

AN - SCOPUS:0031879369

VL - 37

SP - 841

EP - 847

JO - Journal of the American Academy of Child and Adolescent Psychiatry

JF - Journal of the American Academy of Child and Adolescent Psychiatry

SN - 0890-8567

IS - 8

ER -