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ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
Juan A. Orellana
, Nicolas Froger
, Pascal Ezan
,
Jean X. Jiang
, Michael V.L. Bennett
, Christian C. Naus
, Christian Giaume
, Juan C. Sáez
Department of Biochemistry & Structural Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
335
Scopus citations
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Medicine and Dentistry
Neuron
100%
Astrocyte
75%
Hypoxia
50%
Adenosine Triphosphate
37%
Glutamic Acid
37%
Microglia
37%
Receptor
25%
Serositis
25%
Glucose
25%
Diabetes
25%
Alzheimer's Disease
25%
Cells
25%
Nervous System
25%
Tumor Necrosis Factor
25%
Amyloid
12%
Peptide
12%
Receptor Antagonist
12%
Cell Communication
12%
Ischemia
12%
Connexin 43
12%
Brain Ischemia
12%
Neurodegeneration
12%
NMDA Receptor
12%
Mortality
12%
Purinergic P2X Receptor
12%
Death
12%
Neuroscience
Astrocyte
75%
Pannexin
50%
Microglia
37%
Adenosine Triphosphate
37%
Glutamic Acid
37%
Eicosanoid Receptor
25%
Glucose
25%
Diabetes
25%
Peptide
12%
Receptor Antagonist
12%
Cell Communication
12%
Amyloid
12%
Ischemia
12%
Neurodegeneration
12%
Neuronal Death
12%
Connexin 43
12%
NMDA Receptor
12%
Purinergic P2X Receptor
12%
Brain
12%