Assignment of the gene for carboxypeptidase A to human chromosome 7q22→qter and to mouse chromosome 6

N. K. Honey, A. Y. Sakaguchi, P. A. Lalley, C. Quinto, W. J. Rutter, S. L. Naylor

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

A rat cDNA probe for preprocarboxypeptidase A was used to follow the segregation of the human gene for carboxypeptidase A (CPA) in 49 human x mouse somatic cell hybrids using Southern filter hybridization techniques. CPA was assigned to human chromosome 7q22→qter. Similarly, the probe was used to follow the segregation of the mouse gene for carboxypeptidase A (Cpa) in 19 mouse x Chinese hamster somatic cell hybrids. Cpa was assigned to mouse chromosome 6. The gene for carboxypeptidase A forms part of a syntenic group that is conserved in man and mouse.

Original languageEnglish (US)
Pages (from-to)27-31
Number of pages5
JournalHuman Genetics
Volume72
Issue number1
DOIs
StatePublished - Jan 1986
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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