Assessment of hemodynamics in debakey type III aortic dissections for planning surgical interventions and to understand post-treatment changes

Christof Karmonik, Jean Bismuth, Mark G. Davies, Dipan J. Shah, Alan B. Lumsden

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Aortic dissections are a lethal disease affecting thousands of people in the USA each year. This chapter illustrates the application of personalized computational fluid dynamics (CFD) in understanding the hemodynamics of DeBakey type III/Stanford B aortic dissections (dissections confined to the descending aorta), pre-and post-surgical interventions, and simulating hemodynamic changes as a pretreatment planning tool. In this regard, CFD simulations using patient-derived data may be useful for gaining a conceptual understanding of the hemodynamic factors for a particular aortic dissection before intervention and how these factors change with treatment or disease progression. CFD simulations have a potential role in evaluating a number of scenarios and configurations, guiding therapy, and providing a basis for outcome prediction.

Original languageEnglish (US)
Title of host publicationComputational Surgery and Dual Training
Subtitle of host publicationComputing, Robotics and Imaging
PublisherSpringer New York
Pages241-256
Number of pages16
ISBN (Electronic)9781461486480
ISBN (Print)9781461486473
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

Keywords

  • Aortic dissections
  • Cardiovascular disease
  • Computational fluid dynamic
  • False lumen
  • Fenestration
  • Hemodynamics
  • Pressure catheter
  • Retrograde flow
  • Surgical planning
  • TEVAR
  • Thrombosis
  • Transcient flow
  • Wall shear stress

ASJC Scopus subject areas

  • Engineering(all)

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