Assessment of Antral Protective Mechanisms and Intestinal Susceptibility Gradient to Ulcer Formation

H. D. Root, N. W. Crisp, C. Jenson, K. Imamoglu, O. H. Wangensteen

Research output: Contribution to journalArticlepeer-review

Abstract

1) In Group II type of preparation described herein (antral exclusion with 50% of acid peptic secreting tissue attached to antrum) no abettment of ulcer diathesis was noted. Ulcer was not observed at either neostoma. 2) When, however, a similar fundic pouch was attached to the duodenum (Group I preparation) ulcer occurred at this neostoma in 50% of dogs studied and interestingly not in the short duodenal segment, but just over on the jejunal side, an occurrence which suggests an increased gradient of susceptibility to peptic ulceration.

Original languageEnglish (US)
Pages (from-to)437-440
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume102
Issue number2
DOIs
StatePublished - Nov 1959
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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