A series of novel bischelate bridging ligands, CH3NH(CH 2)2N(CH3)(CH2) n N(CH3)(CH2)2NHCH3 (n = 9, 10, 11, and 12) were synthesized as hydrochloride salts and characterized by elemental analyses, electrospray mass spectrometry, and 1H and 13C NMR spectroscopy. These ligands form pseudorotaxanes with α-cyclodextrin (α-CD) and the stability constants have been determined from 1H NMR titrations in D2O. The kinetics and mechanism of the assembly and dissociation of a pseudorotaxane in which α-CD has been threaded by the CH3NH2(CH 2)2N(CH3)(CH2)12N(CH 3)(CH2)2NH2CH 3 2+ ligand were determined in aqueous solution using 1H NMR spectroscopy. A weak inclusion of the dimethylethylenediamine end group precedes the passage of the α-CD onto the hydrophobic dodecamethylene chain.
|Original language||English (US)|
|Number of pages||7|
|Journal||Journal of Inclusion Phenomena|
|State||Published - Nov 2005|
ASJC Scopus subject areas
- Food Science
- Condensed Matter Physics