Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease

P. Lewis White; Stephane Bretagne; Angela M. Caliendo; Juergen Loeffler; Thomas F. Patterson; Monica Slavin; John R. Wingard

doi:10.1093/cid/ciaa1865

Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease

P. Lewis White, Stephane Bretagne, Angela M. Caliendo, Juergen Loeffler, Thomas F. Patterson, Monica Slavin, John R. Wingard

Division of Infectious Diseases

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Aspergillus polymerase chain reaction testing of blood and respiratory samples has recently been included in the second revision of the EORTC/MSGERC definitions for classifying invasive fungal disease. This is a result of considerable efforts to standardize methodology, the availability of commercial assays and external quality control programs, and additional clinical validation. This supporting article provides both clinical and technical justifications for its inclusion while also summarizing recent advances and likely future developments in the molecular diagnosis of invasive aspergillosis.

Original language	English (US)
Pages (from-to)	S95-S101
Journal	Clinical Infectious Diseases
Volume	72
DOIs	https://doi.org/10.1093/cid/ciaa1865
State	Published - Mar 15 2021

Keywords

Aspergillus PCR
EORTC/MSGERC definitions
clinical performance
technical aspects

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Access to Document

10.1093/cid/ciaa1865

Fingerprint

Dive into the research topics of 'Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease'. Together they form a unique fingerprint.

Cite this

White, P. L., Bretagne, S., Caliendo, A. M., Loeffler, J., Patterson, T. F., Slavin, M., & Wingard, J. R. (2021). Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease. Clinical Infectious Diseases, 72, S95-S101. https://doi.org/10.1093/cid/ciaa1865

Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease. / White, P. Lewis; Bretagne, Stephane; Caliendo, Angela M. et al.
In: Clinical Infectious Diseases, Vol. 72, 15.03.2021, p. S95-S101.

Research output: Contribution to journal › Article › peer-review

White, PL, Bretagne, S, Caliendo, AM, Loeffler, J, Patterson, TF, Slavin, M & Wingard, JR 2021, 'Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease', Clinical Infectious Diseases, vol. 72, pp. S95-S101. https://doi.org/10.1093/cid/ciaa1865

White PL, Bretagne S, Caliendo AM, Loeffler J, Patterson TF, Slavin M et al. Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease. Clinical Infectious Diseases. 2021 Mar 15;72:S95-S101. doi: 10.1093/cid/ciaa1865

@article{79ede623f2b44a4f9663bbbe70808438,

title = "Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease",

abstract = "Aspergillus polymerase chain reaction testing of blood and respiratory samples has recently been included in the second revision of the EORTC/MSGERC definitions for classifying invasive fungal disease. This is a result of considerable efforts to standardize methodology, the availability of commercial assays and external quality control programs, and additional clinical validation. This supporting article provides both clinical and technical justifications for its inclusion while also summarizing recent advances and likely future developments in the molecular diagnosis of invasive aspergillosis.",

keywords = "Aspergillus PCR, EORTC/MSGERC definitions, clinical performance, technical aspects",

author = "White, {P. Lewis} and Stephane Bretagne and Caliendo, {Angela M.} and Juergen Loeffler and Patterson, {Thomas F.} and Monica Slavin and Wingard, {John R.}",

note = "Publisher Copyright: {\textcopyright} 2021 The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.",

year = "2021",

month = mar,

day = "15",

doi = "10.1093/cid/ciaa1865",

language = "English (US)",

volume = "72",

pages = "S95--S101",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

}

TY - JOUR

T1 - Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease

AU - White, P. Lewis

AU - Bretagne, Stephane

AU - Caliendo, Angela M.

AU - Loeffler, Juergen

AU - Patterson, Thomas F.

AU - Slavin, Monica

AU - Wingard, John R.

N1 - Publisher Copyright: © 2021 The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

PY - 2021/3/15

Y1 - 2021/3/15

N2 - Aspergillus polymerase chain reaction testing of blood and respiratory samples has recently been included in the second revision of the EORTC/MSGERC definitions for classifying invasive fungal disease. This is a result of considerable efforts to standardize methodology, the availability of commercial assays and external quality control programs, and additional clinical validation. This supporting article provides both clinical and technical justifications for its inclusion while also summarizing recent advances and likely future developments in the molecular diagnosis of invasive aspergillosis.

AB - Aspergillus polymerase chain reaction testing of blood and respiratory samples has recently been included in the second revision of the EORTC/MSGERC definitions for classifying invasive fungal disease. This is a result of considerable efforts to standardize methodology, the availability of commercial assays and external quality control programs, and additional clinical validation. This supporting article provides both clinical and technical justifications for its inclusion while also summarizing recent advances and likely future developments in the molecular diagnosis of invasive aspergillosis.

KW - Aspergillus PCR

KW - EORTC/MSGERC definitions

KW - clinical performance

KW - technical aspects

UR - http://www.scopus.com/inward/record.url?scp=85102838859&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85102838859&partnerID=8YFLogxK

U2 - 10.1093/cid/ciaa1865

DO - 10.1093/cid/ciaa1865

M3 - Article

C2 - 33709129

AN - SCOPUS:85102838859

SN - 1058-4838

VL - 72

SP - S95-S101

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

ER -

Aspergillus Polymerase Chain Reaction-An Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this