Arcus-anchored acellular dermal graft compared to anterior colporrhaphy for stage II cystoceles and beyond

Sylvia M. Botros, Peter K. Sand, Jennifer L. Beaumont, Yoram Abramov, Jay James Miller, Roger P. Goldberg

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Introduction and hypothesis: The aim of this study is to compare acellular dermal matrix to standard colporrhaphy for cystocele repair. Methods: One hundred two patients with greater than or equal to stage II anterior prolapse (Aa or Ba 0) who underwent anterior colporrhaphy with acellular dermal implant attached to the arcus between October 2003 and February 2007 were compared to 89 controls who received standard anterior colporrhaphy. Objective recurrence was defined as greater than or equal to stage II (Aa or Ba -1). Results: The dermal graft and colporrhaphy groups were comparable in age, parity, body mass index, and concomitant surgeries except hysteropexy and hysterectomy. Regression was performed for possible confounders. Postoperatively, 14 (19%) recurrences were identified in the dermal graft group vs. 26 (43%) in the colporrhaphy group (p = 0.004). Two patients underwent reoperations for cystocele recurrence in the study group vs. four in the control group. Time to normal voiding, subjective stress urinary incontinence, estimated blood loss, and length of hospital stay did not differ between groups. Conclusion: Dermal acellular matrix provides benefit over standard colporrhaphy.

Original languageEnglish (US)
Pages (from-to)1265-1271
Number of pages7
JournalInternational Urogynecology Journal
Issue number10
StatePublished - 2009
Externally publishedYes


  • Acellular dermal graft
  • Anterior colporrhaphy
  • Cystocele repair
  • Graft materials
  • Prolapse repair

ASJC Scopus subject areas

  • Urology
  • Obstetrics and Gynecology


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