Approaches to cloning of pain-related ion channel genes

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Molecular pain research is a relatively new and rapidly expanding field that represents advancement in conventional pain research. One of the fundamentals of molecular pain involves the cloning of genes and especially the ion channels specifically involved in nociceptive processing at the periphery and centrally. A variety of approaches were used to isolate these critically important genes. Cloning of these genes involved innovative strategies based on existing molecular approaches. This review will discuss well-utilized cloning approaches and their exploitation in molecular pain research.

Original languageEnglish (US)
Title of host publicationMethods in Molecular Biology
Pages3-19
Number of pages17
Volume998
DOIs
StatePublished - 2013

Publication series

NameMethods in Molecular Biology
Volume998
ISSN (Print)10643745

Fingerprint

Ion Channels
Organism Cloning
Pain
Genes
Research

Keywords

  • Differential cloning
  • Expression cloning
  • Functional cloning
  • Homology cloning
  • Molecular pain research
  • Subtractive cloning

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

Cite this

Akopian, A. N. (2013). Approaches to cloning of pain-related ion channel genes. In Methods in Molecular Biology (Vol. 998, pp. 3-19). (Methods in Molecular Biology; Vol. 998). https://doi.org/10.1007/978-1-62703-351-0_1

Approaches to cloning of pain-related ion channel genes. / Akopian, Armen N.

Methods in Molecular Biology. Vol. 998 2013. p. 3-19 (Methods in Molecular Biology; Vol. 998).

Research output: Chapter in Book/Report/Conference proceedingChapter

Akopian, AN 2013, Approaches to cloning of pain-related ion channel genes. in Methods in Molecular Biology. vol. 998, Methods in Molecular Biology, vol. 998, pp. 3-19. https://doi.org/10.1007/978-1-62703-351-0_1
Akopian AN. Approaches to cloning of pain-related ion channel genes. In Methods in Molecular Biology. Vol. 998. 2013. p. 3-19. (Methods in Molecular Biology). https://doi.org/10.1007/978-1-62703-351-0_1
Akopian, Armen N. / Approaches to cloning of pain-related ion channel genes. Methods in Molecular Biology. Vol. 998 2013. pp. 3-19 (Methods in Molecular Biology).
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