Approaches in the chemoprevention of breast cancer

Kararickal V. Dileep, Michelle Kelly, Elizabeth Hardin, Chittalakkottu Sadasivan, Hareesh B. Nair

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Nanotechnology in bioscience and therapeutics has advanced tremendously in this decade. Many nanoparticle formulations as well as passive and active targeted agents have been developed and proved effective preclinically in proof-of-concept models of different cancers.Many of these formulations use polymer nanoparticles, liposomes, bubkyballs, fullerenes, carbon nanotubes, dendrimers, isotope tags, and PEG compounds. In effect, nanoparticle formulations have become the norm in chemoprevention. In this paper we review nanoformulations of bioactive compounds that have been tested for their potential mechanistic antiproliferative activity in breast cancer. We also discuss the possibility of enhancing the activity of these compounds using different innovative bioconjugation methods.

Original languageEnglish (US)
Pages (from-to)282-288
Number of pages7
JournalJournal of Cancer Science and Therapy
Issue number8
StatePublished - 2013
Externally publishedYes


  • Breast cancer
  • Chemoprevention
  • Mammography

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


Dive into the research topics of 'Approaches in the chemoprevention of breast cancer'. Together they form a unique fingerprint.

Cite this