Abstract
Antithrombin III polymorphism was observed in the gray short-tailed opossum, Monodelphis domestica, by either one-dimensional polyacrylamide gel electrophoresis (PAGE; pH 7.9), two-dimensional PAGE (agarose, pH 5.4; 12% T, pH 7.9), or isoelectric focusing (pH 4.2–4.9) followed by immunoblotting with rabbit antiserum to human antithrombin III. Family studies demonstrated an inheritance of three codominant autosomal alleles, AT3A, AT3B, and AT3C, and a population study revealed frequencies of 0.70, 0.10, and 0.20, respectively.
Original language | English (US) |
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Pages (from-to) | 591-601 |
Number of pages | 11 |
Journal | Biochemical Genetics |
Volume | 30 |
Issue number | 11 |
DOIs | |
State | Published - 1992 |
Externally published | Yes |
Keywords
- antithrombin III
- genetics
- Monodelphis domestica
- polymorphism
ASJC Scopus subject areas
- Ecology, Evolution, Behavior and Systematics
- Biochemistry
- Genetics
- Molecular Biology