Abstract
Antithrombin III polymorphism was observed in the gray short-tailed opossum, Monodelphis domestica, by either one-dimensional polyacrylamide gel electrophoresis (PAGE; pH 7.9), two-dimensional PAGE (agarose, pH 5.4; 12% T, pH 7.9), or isoelectric focusing (pH 4.2–4.9) followed by immunoblotting with rabbit antiserum to human antithrombin III. Family studies demonstrated an inheritance of three codominant autosomal alleles, AT3A, AT3B, and AT3C, and a population study revealed frequencies of 0.70, 0.10, and 0.20, respectively.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 591-601 |
| Number of pages | 11 |
| Journal | Biochemical Genetics |
| Volume | 30 |
| Issue number | 11 |
| DOIs | |
| State | Published - 1992 |
| Externally published | Yes |
Keywords
- antithrombin III
- genetics
- Monodelphis domestica
- polymorphism
ASJC Scopus subject areas
- Ecology, Evolution, Behavior and Systematics
- Biochemistry
- Genetics
- Molecular Biology
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Cite this
Bell, K., Arthur, H., van Oorschot, R. A. H., & VandeBerg, J. L. (1992). Antithrombin III (AT3) polymorphism in the marsupial Monodelphis domestica: Identification and genetics. Biochemical Genetics, 30(11), 591-601. https://doi.org/10.1007/PL00020520