Antithrombin III (AT3) polymorphism in the marsupial Monodelphis domestica

Identification and genetics

Kevin Bell, Helen Arthur, Roland A H van Oorschot, John L. VandeBerg

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Antithrombin III polymorphism was observed in the gray short-tailed opossum, Monodelphis domestica, by either one-dimensional polyacrylamide gel electrophoresis (PAGE; pH 7.9), two-dimensional PAGE (agarose, pH 5.4; 12% T, pH 7.9), or isoelectric focusing (pH 4.2-4.9) followed by immunoblotting with rabbit antiserum to human antithrombin III. Family studies demonstrated an inheritance of three codominant autosomal alleles, AT3A, AT3B, and AT3C, and a population study revealed frequencies of 0.70, 0.10, and 0.20, respectively.

Original languageEnglish (US)
Pages (from-to)591-601
Number of pages11
JournalBiochemical Genetics
Volume30
Issue number11-12
DOIs
StatePublished - Dec 1992
Externally publishedYes

Fingerprint

Monodelphis
Monodelphis domestica
Marsupialia
Antithrombin III
marsupial
Metatheria
Polymorphism
electrokinesis
allele
polymorphism
gel
genetic polymorphism
polyacrylamide gel electrophoresis
Electrophoresis
Sepharose
Immune Sera
family studies
isoelectric focusing
Isoelectric Focusing
opossums

Keywords

  • antithrombin III
  • genetics
  • Monodelphis domestica
  • polymorphism

ASJC Scopus subject areas

  • Genetics
  • Biochemistry
  • Molecular Biology
  • Ecology, Evolution, Behavior and Systematics

Cite this

Antithrombin III (AT3) polymorphism in the marsupial Monodelphis domestica : Identification and genetics. / Bell, Kevin; Arthur, Helen; van Oorschot, Roland A H; VandeBerg, John L.

In: Biochemical Genetics, Vol. 30, No. 11-12, 12.1992, p. 591-601.

Research output: Contribution to journalArticle

Bell, Kevin ; Arthur, Helen ; van Oorschot, Roland A H ; VandeBerg, John L. / Antithrombin III (AT3) polymorphism in the marsupial Monodelphis domestica : Identification and genetics. In: Biochemical Genetics. 1992 ; Vol. 30, No. 11-12. pp. 591-601.
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