Antithrombin III activity in baboons

Milka M. Montiel; David L. McGlasson

doi:10.1007/BF02382805

Antithrombin III activity in baboons

Milka M. Montiel, David L. McGlasson

Research output: Contribution to journal › Article › peer-review

Abstract

The antithrombin III-heparin cofactor activity of 65 baboons and 130 healthy human subjects was measured. The results indicate that antithrombin III-heparin cofactor activity is significantly lower in baboons than in humans. The increased activity of the coagulation system of baboon is coupled with decreased antithrombin III-heparin cofactor activity. In humans each of these changes is associated with increased risk of thrombosis, but the baboon has a very low risk of developing thrombosis. Other factors probably balance the coagulation-coagulation inhibition systems in baboons.

Original language	English (US)
Pages (from-to)	371-378
Number of pages	8
Journal	Primates
Volume	19
Issue number	2
DOIs	https://doi.org/10.1007/BF02382805
State	Published - Apr 1978
Externally published	Yes

ASJC Scopus subject areas

Animal Science and Zoology

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10.1007/BF02382805

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abstract = "The antithrombin III-heparin cofactor activity of 65 baboons and 130 healthy human subjects was measured. The results indicate that antithrombin III-heparin cofactor activity is significantly lower in baboons than in humans. The increased activity of the coagulation system of baboon is coupled with decreased antithrombin III-heparin cofactor activity. In humans each of these changes is associated with increased risk of thrombosis, but the baboon has a very low risk of developing thrombosis. Other factors probably balance the coagulation-coagulation inhibition systems in baboons.",

author = "Montiel, {Milka M.} and McGlasson, {David L.}",

year = "1978",

month = apr,

doi = "10.1007/BF02382805",

language = "English (US)",

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journal = "Primates",

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AU - McGlasson, David L.

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AB - The antithrombin III-heparin cofactor activity of 65 baboons and 130 healthy human subjects was measured. The results indicate that antithrombin III-heparin cofactor activity is significantly lower in baboons than in humans. The increased activity of the coagulation system of baboon is coupled with decreased antithrombin III-heparin cofactor activity. In humans each of these changes is associated with increased risk of thrombosis, but the baboon has a very low risk of developing thrombosis. Other factors probably balance the coagulation-coagulation inhibition systems in baboons.

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Antithrombin III activity in baboons

Abstract

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