Antithrombin III activity in baboons

Milka M. Montiel, David L. McGlasson

Research output: Contribution to journalArticlepeer-review


The antithrombin III-heparin cofactor activity of 65 baboons and 130 healthy human subjects was measured. The results indicate that antithrombin III-heparin cofactor activity is significantly lower in baboons than in humans. The increased activity of the coagulation system of baboon is coupled with decreased antithrombin III-heparin cofactor activity. In humans each of these changes is associated with increased risk of thrombosis, but the baboon has a very low risk of developing thrombosis. Other factors probably balance the coagulation-coagulation inhibition systems in baboons.

Original languageEnglish (US)
Pages (from-to)371-378
Number of pages8
Issue number2
StatePublished - Apr 1978
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology


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