Antisocial personality disorder and aggression in recently abstinent cocaine dependent subjects

F. Gerard Moeller, Donald M. Dougherty, Terry Rustin, Alan C. Swann, Terry J. Allen, Nurun Shah, Don R. Cherek

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


To study the relationship between cocaine abstinence symptoms, personality, and aggression, we used the ®Point Subtraction Aggression Paradigm (PSAP) to measure aggression in 18 subjects admitted for the treatment of cocaine dependence. Eight subjects met criteria for antisocial personality disorder (ASPD). There was a significant correlation between presence of ASPD and frequency of aggressive responding by stepwise multiple regression. When presence of ASPD was factored out of the correlations, there was no significant relationship between aggressive responding and cocaine craving, withdrawal symptoms, amount of cocaine used, or length of time since use. These preliminary results suggest that in cocaine dependent individuals seeking treatment, current aggression is most dependent on the individual's previous aggressive behavior.

Original languageEnglish (US)
Pages (from-to)175-182
Number of pages8
JournalDrug and Alcohol Dependence
Issue number2-3
StatePublished - Mar 14 1997
Externally publishedYes


  • Aggression
  • Antisocial personality disorder
  • Cocaine
  • Human

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)


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