Antisocial personality disorder and aggression in recently abstinent cocaine dependent subjects

F. Gerard Moeller; Donald M. Dougherty; Terry Rustin; Alan C. Swann; Terry J. Allen; Nurun Shah; Don R. Cherek

doi:10.1016/S0376-8716(96)01335-X

Antisocial personality disorder and aggression in recently abstinent cocaine dependent subjects

F. Gerard Moeller, Donald M. Dougherty, Terry Rustin, Alan C. Swann, Terry J. Allen, Nurun Shah, Don R. Cherek

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

To study the relationship between cocaine abstinence symptoms, personality, and aggression, we used the ®Point Subtraction Aggression Paradigm (PSAP) to measure aggression in 18 subjects admitted for the treatment of cocaine dependence. Eight subjects met criteria for antisocial personality disorder (ASPD). There was a significant correlation between presence of ASPD and frequency of aggressive responding by stepwise multiple regression. When presence of ASPD was factored out of the correlations, there was no significant relationship between aggressive responding and cocaine craving, withdrawal symptoms, amount of cocaine used, or length of time since use. These preliminary results suggest that in cocaine dependent individuals seeking treatment, current aggression is most dependent on the individual's previous aggressive behavior.

Original language	English (US)
Pages (from-to)	175-182
Number of pages	8
Journal	Drug and Alcohol Dependence
Volume	44
Issue number	2-3
DOIs	https://doi.org/10.1016/S0376-8716(96)01335-X
State	Published - Mar 14 1997
Externally published	Yes

Keywords

Aggression
Antisocial personality disorder
Cocaine
Human

ASJC Scopus subject areas

Toxicology
Pharmacology
Psychiatry and Mental health
Pharmacology (medical)

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title = "Antisocial personality disorder and aggression in recently abstinent cocaine dependent subjects",

abstract = "To study the relationship between cocaine abstinence symptoms, personality, and aggression, we used the {\textregistered}Point Subtraction Aggression Paradigm (PSAP) to measure aggression in 18 subjects admitted for the treatment of cocaine dependence. Eight subjects met criteria for antisocial personality disorder (ASPD). There was a significant correlation between presence of ASPD and frequency of aggressive responding by stepwise multiple regression. When presence of ASPD was factored out of the correlations, there was no significant relationship between aggressive responding and cocaine craving, withdrawal symptoms, amount of cocaine used, or length of time since use. These preliminary results suggest that in cocaine dependent individuals seeking treatment, current aggression is most dependent on the individual's previous aggressive behavior.",

keywords = "Aggression, Antisocial personality disorder, Cocaine, Human",

author = "Moeller, {F. Gerard} and Dougherty, {Donald M.} and Terry Rustin and Swann, {Alan C.} and Allen, {Terry J.} and Nurun Shah and Cherek, {Don R.}",

note = "Funding Information: Supported in part by the Harris County Psychiatric Center, National Institute on Drug Abuse grant # DA 03166-10, # DA 08425-01, and at the time the study was conducted Donald M. Dougherty was supported by the National Institute on Drug Abuse training grant # DA 07247.",

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AU - Moeller, F. Gerard

AU - Dougherty, Donald M.

AU - Rustin, Terry

AU - Swann, Alan C.

AU - Allen, Terry J.

AU - Shah, Nurun

AU - Cherek, Don R.

N1 - Funding Information: Supported in part by the Harris County Psychiatric Center, National Institute on Drug Abuse grant # DA 03166-10, # DA 08425-01, and at the time the study was conducted Donald M. Dougherty was supported by the National Institute on Drug Abuse training grant # DA 07247.

PY - 1997/3/14

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N2 - To study the relationship between cocaine abstinence symptoms, personality, and aggression, we used the ®Point Subtraction Aggression Paradigm (PSAP) to measure aggression in 18 subjects admitted for the treatment of cocaine dependence. Eight subjects met criteria for antisocial personality disorder (ASPD). There was a significant correlation between presence of ASPD and frequency of aggressive responding by stepwise multiple regression. When presence of ASPD was factored out of the correlations, there was no significant relationship between aggressive responding and cocaine craving, withdrawal symptoms, amount of cocaine used, or length of time since use. These preliminary results suggest that in cocaine dependent individuals seeking treatment, current aggression is most dependent on the individual's previous aggressive behavior.

AB - To study the relationship between cocaine abstinence symptoms, personality, and aggression, we used the ®Point Subtraction Aggression Paradigm (PSAP) to measure aggression in 18 subjects admitted for the treatment of cocaine dependence. Eight subjects met criteria for antisocial personality disorder (ASPD). There was a significant correlation between presence of ASPD and frequency of aggressive responding by stepwise multiple regression. When presence of ASPD was factored out of the correlations, there was no significant relationship between aggressive responding and cocaine craving, withdrawal symptoms, amount of cocaine used, or length of time since use. These preliminary results suggest that in cocaine dependent individuals seeking treatment, current aggression is most dependent on the individual's previous aggressive behavior.

KW - Aggression

KW - Antisocial personality disorder

KW - Cocaine

KW - Human

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Antisocial personality disorder and aggression in recently abstinent cocaine dependent subjects

Abstract

Keywords

ASJC Scopus subject areas

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