Antioxidant supplementation in chronic pancreatitis: Current evidence an overview

Natalia Hernandez, Nicholas Perez, Sandeep Patel, Laura Rosenkranz

Research output: Contribution to journalArticlepeer-review


Chronic pancreatitis is a complex disease, with a 4-fold increase in mortality and has a colossal personal, social and economic impact. Pain is its debilitating manifestation that remains a serious medical challenge with limited treatment options. Great efforts have been focused on investigating the mechanisms of chronic pain with the main objective being to find the ways to improve quality of life in patients. There is evidence suggesting that oxidative stress is one of the factors responsible for pancreatic inflammation, which results in pain. The interest has been directed to the nutrients possessing antioxidant and anti-inflammatory properties in attempt to diminish oxidative pancreatic damage and improve the debilitating manifestations. This review will focus on the accumulated evidence and recent progress in understanding the role of the nutritional components in the management of chronic pancreatitis.

Original languageEnglish (US)
Pages (from-to)47-52
Number of pages6
JournalPractical Gastroenterology
Issue number12
StatePublished - Dec 2011

ASJC Scopus subject areas

  • Gastroenterology


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