Antidepressant-like effects of delta opioid receptor agonists

Emily M. Jutkiewicz, James H. Woods

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations


Endogenous opioids and exogenously administered delta opioid receptor agonists have been demonstrated to have antidepressant-like effects in animal models used to evaluate novel antidepressant compounds. This chapter reviews some of the previous research investigating the role of the opioid system, and more specifically the delta opioid receptor system, in clinical depression and in animal models used to study human depression and antidepressant treatments. In addition, this chapter discusses the interpretation of animal models of depression and their uses in the evaluation of new potential therapeutics.

Original languageEnglish (US)
Title of host publicationThe Delta Receptor
PublisherCRC Press
Number of pages17
ISBN (Electronic)9780203025765
ISBN (Print)9780824740313
StatePublished - Jan 1 2003
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Health Professions(all)
  • Medicine(all)


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