Antidepressant drugs

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations


This review covers the efficacy, side effects, and toxicity of various classes of antidepressants: tricyclics (TCAs), monoamine oxidase inhibitors (MAOIs), and second generation antidepressants including the selective inhibitors of serotonin reuptake (SSRIs). Also reviewed are newer drugs such as moclobemide, a reversible inhibitor of monoamine oxidase (RIMA), and venlafaxine, a drug that inhibits the uptake of both norepinephrine and serotonin (similar in this respect to a number of the TCAs) but has a side‐effect profile more like that of the SSRIs. Depression 2:1–19 (1994). © 1994 Wiley‐Liss, Inc.

Original languageEnglish (US)
Pages (from-to)1-19
Number of pages19
Issue number1
StatePublished - 1994


  • antidepressants
  • moclobemide
  • monoamine oxidase inhibitors
  • second generation antidepressants
  • selective serotonin reuptake inhibitors
  • tricyclic antidepressants
  • venlafaxine

ASJC Scopus subject areas

  • Psychiatry and Mental health


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