Antibacterial activity of the new glycopeptide antibiotic SKF104662

J. H. Jorgensen, J. S. Redding, L. A. Maher

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The inhibitory activity of the new glycopeptide antibiotic SKF104662 was generally equivalent (±1 concentration increment) to the activities of vancomycin, teicoplanin, and daptomycin against selected gram-positive bacteria. However, SKF104662 demonstrated greater activity against Staphylococcus epidermidis and S. haemolyticus than did teicoplanin and was more active than the other drugs against Clostridium difficile isolates. SKF104662 possessed bactericidal activity quite similar to that of vancomycin against selected isolates of Staphylococcus, Streptococcus, and Enterococcus species.

Original languageEnglish (US)
Pages (from-to)560-561
Number of pages2
JournalAntimicrobial agents and chemotherapy
Volume33
Issue number4
DOIs
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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