Antibacterial activities of antineoplastic agents

C. A. Bodet, J. H. Jorgensen, D. J. Drutz

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

Fourteen antineoplastic agents were examined for in vitro antibacterial activity against 101 aerobic and anaerobic bacterial isolates representing indigenous human microflora and selected opportunistic pathogens. Only 5-fluorouracil, mitomycin, and etoposide demonstrated inhibitory effects at achievable plasma concentrations, while the remaining drugs lacked appreciable antibacterial activities.

Original languageEnglish (US)
Pages (from-to)437-439
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume28
Issue number3
DOIs
StatePublished - Jan 1 1985

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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