Antibacterial activities of antineoplastic agents

C. A. Bodet; J. H. Jorgensen; D. J. Drutz

doi:10.1128/AAC.28.3.437

Antibacterial activities of antineoplastic agents

C. A. Bodet, J. H. Jorgensen, D. J. Drutz

Pathology

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

Fourteen antineoplastic agents were examined for in vitro antibacterial activity against 101 aerobic and anaerobic bacterial isolates representing indigenous human microflora and selected opportunistic pathogens. Only 5-fluorouracil, mitomycin, and etoposide demonstrated inhibitory effects at achievable plasma concentrations, while the remaining drugs lacked appreciable antibacterial activities.

Original language	English (US)
Pages (from-to)	437-439
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	28
Issue number	3
DOIs	https://doi.org/10.1128/AAC.28.3.437
State	Published - Jan 1 1985

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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