Abstract
Background and Purpose: The relation between anterior ischemic optic neuropathy and carotid artery atherosclerotic disease is unclear. We studied patients with anterior ischemic optic neuropathy to determine if they had an increased occurrence of carotid artery stenosis. Methods: Fifteen consecutive patients with anterior ischemic optic neuropathy were evaluated prospectively for cervical carotid artery stenosis and compared with 30 age- and sex-matched asymptomatic patients and also with 11 age- and sex-matched patients experiencing transient monocular blindness. Results: There was no difference in the mean stenosis of the internal carotid artery between patients with anterior ischemic optic neuropathy (mean carotid stenosis, 19%) and asymptomatic patients (mean carotid stenosis, 9%;p>0.05), whereas patients with transient monocular blindness had significantly more stenosis (mean, 77%) in the cervical carotid arteries than both control subjects (p<0.0001) and patients with anterior ischemic optic neuropathy (p<0.0001). There was also no difference in the percentage of patients with stenosis ≥30% in anterior ischemic optic neuropathy (two of 15) and asymptomatic patients (five of 30), whereas 10 of 11 patients with transient monocular blindness had stenoses ≥30%, significantly more than patients with anterior ischemic optic neuropathy (p<0.0001) and asymptomatic patients (p<0.0001). Conclusions: Anterior ischemic optic neuropathy is not a marker for atherosclerotic carotid artery stenosis. The pathogenesis of nonarteritic anterior ischemic optic neuropathy does not involve carotid artery stenosis in most patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 539-542 |
| Number of pages | 4 |
| Journal | Stroke |
| Volume | 24 |
| Issue number | 4 |
| State | Published - Apr 1993 |
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Keywords
- Carotid artery diseases
- Cerebrovascular disorders
- Ultrasonics
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Neuroscience(all)
Cite this
Anterior ischemic optic neuropathy is not associated with carotid artery atherosclerosis. / Fry, Constance L.; Carter, John E.; Kanter, Merrill C.; Tegeler, Charles H.; Tuley, Michael R.
In: Stroke, Vol. 24, No. 4, 04.1993, p. 539-542.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anterior ischemic optic neuropathy is not associated with carotid artery atherosclerosis
AU - Fry, Constance L.
AU - Carter, John E.
AU - Kanter, Merrill C.
AU - Tegeler, Charles H.
AU - Tuley, Michael R.
PY - 1993/4
Y1 - 1993/4
N2 - Background and Purpose: The relation between anterior ischemic optic neuropathy and carotid artery atherosclerotic disease is unclear. We studied patients with anterior ischemic optic neuropathy to determine if they had an increased occurrence of carotid artery stenosis. Methods: Fifteen consecutive patients with anterior ischemic optic neuropathy were evaluated prospectively for cervical carotid artery stenosis and compared with 30 age- and sex-matched asymptomatic patients and also with 11 age- and sex-matched patients experiencing transient monocular blindness. Results: There was no difference in the mean stenosis of the internal carotid artery between patients with anterior ischemic optic neuropathy (mean carotid stenosis, 19%) and asymptomatic patients (mean carotid stenosis, 9%;p>0.05), whereas patients with transient monocular blindness had significantly more stenosis (mean, 77%) in the cervical carotid arteries than both control subjects (p<0.0001) and patients with anterior ischemic optic neuropathy (p<0.0001). There was also no difference in the percentage of patients with stenosis ≥30% in anterior ischemic optic neuropathy (two of 15) and asymptomatic patients (five of 30), whereas 10 of 11 patients with transient monocular blindness had stenoses ≥30%, significantly more than patients with anterior ischemic optic neuropathy (p<0.0001) and asymptomatic patients (p<0.0001). Conclusions: Anterior ischemic optic neuropathy is not a marker for atherosclerotic carotid artery stenosis. The pathogenesis of nonarteritic anterior ischemic optic neuropathy does not involve carotid artery stenosis in most patients.
AB - Background and Purpose: The relation between anterior ischemic optic neuropathy and carotid artery atherosclerotic disease is unclear. We studied patients with anterior ischemic optic neuropathy to determine if they had an increased occurrence of carotid artery stenosis. Methods: Fifteen consecutive patients with anterior ischemic optic neuropathy were evaluated prospectively for cervical carotid artery stenosis and compared with 30 age- and sex-matched asymptomatic patients and also with 11 age- and sex-matched patients experiencing transient monocular blindness. Results: There was no difference in the mean stenosis of the internal carotid artery between patients with anterior ischemic optic neuropathy (mean carotid stenosis, 19%) and asymptomatic patients (mean carotid stenosis, 9%;p>0.05), whereas patients with transient monocular blindness had significantly more stenosis (mean, 77%) in the cervical carotid arteries than both control subjects (p<0.0001) and patients with anterior ischemic optic neuropathy (p<0.0001). There was also no difference in the percentage of patients with stenosis ≥30% in anterior ischemic optic neuropathy (two of 15) and asymptomatic patients (five of 30), whereas 10 of 11 patients with transient monocular blindness had stenoses ≥30%, significantly more than patients with anterior ischemic optic neuropathy (p<0.0001) and asymptomatic patients (p<0.0001). Conclusions: Anterior ischemic optic neuropathy is not a marker for atherosclerotic carotid artery stenosis. The pathogenesis of nonarteritic anterior ischemic optic neuropathy does not involve carotid artery stenosis in most patients.
KW - Carotid artery diseases
KW - Cerebrovascular disorders
KW - Ultrasonics
UR - http://www.scopus.com/inward/record.url?scp=0027529458&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027529458&partnerID=8YFLogxK
M3 - Article
C2 - 8465359
AN - SCOPUS:0027529458
VL - 24
SP - 539
EP - 542
JO - Stroke
JF - Stroke
SN - 0039-2499
IS - 4
ER -