Modelos animales de lesion y reparacion del cerebro en desarrollo

Translated title of the contribution: Animal models of injury and repair in developing brain

Eduardo Cuestas, Alfredo Caceres, Santiago Palacio

Research output: Contribution to journalArticle

Abstract

Brain injury is a major contributor to neonatal morbidity and mortality, a considerable group of these children will develop long term neurological sequels. Despite the great clinical and social significance and the advances in neonatal medicine, no therapy yet does exist that prevent or decrease detrimental effects in cases of neonatal brain injury. Our objective was to review recent research in relation to the hypothesis for repair mechanism in the developing brain, based in animal models that show developmental compensatory mechanisms that promote neural and functional plasticity. A better understanding of these adaptive mechanisms will help clinicians to apply knowledge derived from animals to human clinical situations.

Original languageSpanish
Pages (from-to)177-182
Number of pages6
JournalMedicina
Volume67
Issue number2
StatePublished - Jun 4 2007

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Keywords

  • Developing brain
  • Injury
  • Repair

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cuestas, E., Caceres, A., & Palacio, S. (2007). Modelos animales de lesion y reparacion del cerebro en desarrollo. Medicina, 67(2), 177-182.