Abstract
Brain injury is a major contributor to neonatal morbidity and mortality, a considerable group of these children will develop long term neurological sequels. Despite the great clinical and social significance and the advances in neonatal medicine, no therapy yet does exist that prevent or decrease detrimental effects in cases of neonatal brain injury. Our objective was to review recent research in relation to the hypothesis for repair mechanism in the developing brain, based in animal models that show developmental compensatory mechanisms that promote neural and functional plasticity. A better understanding of these adaptive mechanisms will help clinicians to apply knowledge derived from animals to human clinical situations.
| Original language | Spanish |
|---|---|
| Pages (from-to) | 177-182 |
| Number of pages | 6 |
| Journal | Medicina |
| Volume | 67 |
| Issue number | 2 |
| State | Published - 2007 |
| Externally published | Yes |
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Keywords
- Developing brain
- Injury
- Repair
ASJC Scopus subject areas
- Medicine(all)
Cite this
Modelos animales de lesion y reparacion del cerebro en desarrollo. / Cuestas, Eduardo; Caceres, Alfredo; Palacio, Santiago.
In: Medicina, Vol. 67, No. 2, 2007, p. 177-182.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Modelos animales de lesion y reparacion del cerebro en desarrollo
AU - Cuestas, Eduardo
AU - Caceres, Alfredo
AU - Palacio, Santiago
PY - 2007
Y1 - 2007
N2 - Brain injury is a major contributor to neonatal morbidity and mortality, a considerable group of these children will develop long term neurological sequels. Despite the great clinical and social significance and the advances in neonatal medicine, no therapy yet does exist that prevent or decrease detrimental effects in cases of neonatal brain injury. Our objective was to review recent research in relation to the hypothesis for repair mechanism in the developing brain, based in animal models that show developmental compensatory mechanisms that promote neural and functional plasticity. A better understanding of these adaptive mechanisms will help clinicians to apply knowledge derived from animals to human clinical situations.
AB - Brain injury is a major contributor to neonatal morbidity and mortality, a considerable group of these children will develop long term neurological sequels. Despite the great clinical and social significance and the advances in neonatal medicine, no therapy yet does exist that prevent or decrease detrimental effects in cases of neonatal brain injury. Our objective was to review recent research in relation to the hypothesis for repair mechanism in the developing brain, based in animal models that show developmental compensatory mechanisms that promote neural and functional plasticity. A better understanding of these adaptive mechanisms will help clinicians to apply knowledge derived from animals to human clinical situations.
KW - Developing brain
KW - Injury
KW - Repair
UR - http://www.scopus.com/inward/record.url?scp=34249702824&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34249702824&partnerID=8YFLogxK
M3 - Article
C2 - 17593606
AN - SCOPUS:34249702824
VL - 67
SP - 177
EP - 182
JO - Medicina
JF - Medicina
SN - 0025-7680
IS - 2
ER -