Androgen receptor CAG repeat polymorphism in males of six non-human primate species

James N. Mubiru; Nicole Cavazos; Peggah Hemmat; Magdalena Garcia-Forey; Robert E. Shade; Jeffrey Rogers

doi:10.1111/j.1600-0684.2011.00517.x

Androgen receptor CAG repeat polymorphism in males of six non-human primate species

James N. Mubiru, Nicole Cavazos, Peggah Hemmat, Magdalena Garcia-Forey, Robert E. Shade, Jeffrey Rogers

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Background Androgen receptor [CAG] _n microsatellite has been linked to human diseases. Methods Six non-human primates were genotyped for the [CAG] _n microsatellite. Results Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic. Conclusions Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases.

Original language	English (US)
Pages (from-to)	67-70
Number of pages	4
Journal	Journal of medical primatology
Volume	41
Issue number	1
DOIs	https://doi.org/10.1111/j.1600-0684.2011.00517.x
State	Published - Feb 2012
Externally published	Yes

Keywords

Baboon
Chimpanzee
Macaques
Mangabey
Marmoset
Microsatellite

ASJC Scopus subject areas

Animal Science and Zoology
veterinary(all)

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10.1111/j.1600-0684.2011.00517.x

Cite this

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title = "Androgen receptor CAG repeat polymorphism in males of six non-human primate species",

abstract = "Background Androgen receptor [CAG] n microsatellite has been linked to human diseases. Methods Six non-human primates were genotyped for the [CAG] n microsatellite. Results Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic. Conclusions Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases.",

keywords = "Baboon, Chimpanzee, Macaques, Mangabey, Marmoset, Microsatellite",

author = "Mubiru, {James N.} and Nicole Cavazos and Peggah Hemmat and Magdalena Garcia-Forey and Shade, {Robert E.} and Jeffrey Rogers",

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language = "English (US)",

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AU - Mubiru, James N.

AU - Cavazos, Nicole

AU - Hemmat, Peggah

AU - Garcia-Forey, Magdalena

AU - Shade, Robert E.

AU - Rogers, Jeffrey

PY - 2012/2

Y1 - 2012/2

N2 - Background Androgen receptor [CAG] n microsatellite has been linked to human diseases. Methods Six non-human primates were genotyped for the [CAG] n microsatellite. Results Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic. Conclusions Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases.

AB - Background Androgen receptor [CAG] n microsatellite has been linked to human diseases. Methods Six non-human primates were genotyped for the [CAG] n microsatellite. Results Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic. Conclusions Non-human primates that are polymorphic for the microsatellite are candidate animal models for CAG-related diseases.

KW - Baboon

KW - Chimpanzee

KW - Macaques

KW - Mangabey

KW - Marmoset

KW - Microsatellite

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Androgen receptor CAG repeat polymorphism in males of six non-human primate species

Abstract

Keywords

ASJC Scopus subject areas

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