Abstract
A review of the literature involving anaphylactoid reactions to iodinated contrast material (ICM) suggests that the reactions are nonantibody-mediated but that a complex activation of inflammatory mediators occurs. Histamine release and/or complement activation has been demonstrated in both in vitro and in vivo experimental systems. It appears that pretreatment of selected cases (those patients previously exhibiting an anaphylactoid reaction) is effective in reducing the frequency and seventy of subsequent reactions when readministration is necessary.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 174-180 |
| Number of pages | 7 |
| Journal | The Journal of Allergy and Clinical Immunology |
| Volume | 62 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 1978 |
| Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology