Analysis of Y chromosome nucleolar organizer mutants in Drosophilamelanogaster

Varsha V. Gandhi, Zelton D. Sharp, James D. Procunier

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Five Y chromosome nucleolar organizer (Y-NO) mutants were analyzed with respect to their rRNA gene numbers, phenotypes and additivity tests with other NO mutants. Four of these are indicative of a class of mutants in which most of the rRNA genes are transcribing functional rRNA. The other mutant has 80 genes, however, lethality and additivity tests suggests that many if not all of these rRNA genes are non-functional. The basis for the observed suppression of rRNA genes of the Y-NO region is discussed.

Original languageEnglish (US)
Pages (from-to)778-784
Number of pages7
JournalBiochemical and Biophysical Research Communications
Issue number2
StatePublished - Jan 29 1982
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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