Análisis de las regiones de predisposición a la psoriasis en la población Española: Evidencia de un gen principal implicado en la psoriasis en la regiõn 6p21

Translated title of the contribution: Analysis of the susceptibility regions to psoriasis in Spanish population: Evidence of a major gene involved in psoriasis in 6p21

Rafael De Cid, Víctor Volpini, Laura Almasy, David Otero, Xavier Estivill, Conxi Lázaro, E. Barberà, C. Ferrándiz, A. Giménez Arnau, F. Grimalt, S. Puig, A. Sánchez, A. Palacios, J. A. Pujol, M. Sánchez, E. Simal, F. Vázquez, B. Ramírez

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations

    Abstract

    BACKGROUND: Identification of the susceptibility regions to psoriasis in Spanish population. Analysis of the chromosomal regions 6p, 17q, 4q and 1cen-q21. PATIENTS AND METHOD: Analysis of 27 Spanish families with psoriasis. Parametric and non-parametric linkage analysis with 22 polymorphic microsatellite markers in the candidate regions. RESULTS: Evidence of linkage (p < 0,05) using non-parametric methods in chromosome 6p. Absence of linkage in 17q, 4q and 1cen-q21 regions. CONCLUSION: We present the evidence of a major gene in 6p21.3 involved in psoriasis in Spanish population.

    Translated title of the contributionAnalysis of the susceptibility regions to psoriasis in Spanish population: Evidence of a major gene involved in psoriasis in 6p21
    Original languageSpanish
    Pages (from-to)49-51
    Number of pages3
    JournalMedicina Clinica
    Volume117
    Issue number2
    DOIs
    StatePublished - Jun 16 2001

    Keywords

    • Candidate genes
    • Genetic linkage
    • Psoriasis

    ASJC Scopus subject areas

    • Medicine(all)

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