Análisis de las regiones de predisposición a la psoriasis en la población Española: Evidencia de un gen principal implicado en la psoriasis en la regiõn 6p21

Translated title of the contribution: Analysis of the susceptibility regions to psoriasis in Spanish population: Evidence of a major gene involved in psoriasis in 6p21

Rafael De Cid, Víctor Volpini, Laura Almasy, David Otero, Xavier Estivill, Conxi Lázaro, E. Barberà, C. Ferrándiz, A. Giménez Arnau, F. Grimalt, S. Puig, A. Sánchez, A. Palacios, J. A. Pujol, M. Sánchez, E. Simal, F. Vázquez, B. Ramírez

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

BACKGROUND: Identification of the susceptibility regions to psoriasis in Spanish population. Analysis of the chromosomal regions 6p, 17q, 4q and 1cen-q21. PATIENTS AND METHOD: Analysis of 27 Spanish families with psoriasis. Parametric and non-parametric linkage analysis with 22 polymorphic microsatellite markers in the candidate regions. RESULTS: Evidence of linkage (p < 0,05) using non-parametric methods in chromosome 6p. Absence of linkage in 17q, 4q and 1cen-q21 regions. CONCLUSION: We present the evidence of a major gene in 6p21.3 involved in psoriasis in Spanish population.

Translated title of the contributionAnalysis of the susceptibility regions to psoriasis in Spanish population: Evidence of a major gene involved in psoriasis in 6p21
Original languageSpanish
Pages (from-to)49-51
Number of pages3
JournalMedicina Clinica
Volume117
Issue number2
DOIs
StatePublished - Jun 16 2001
Externally publishedYes

Keywords

  • Candidate genes
  • Genetic linkage
  • Psoriasis

ASJC Scopus subject areas

  • Medicine(all)

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