Analysis of changes in coagulation factors after postoperative blood loss in burn and non-burn patients

P. Chang, D. J. Murray, J. D. Olson, B. J. Pennell, R. W. Lewis, G. P. Kealey

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A prospective study of the postoperative kinetics of coagulation factors was undertaken in 23 burn patients and in six non-burn patients. All procedures resulted in a large volume blood loss. Fibrinogen, platelets and factors V, VIII and IX were measured serially. Burn patients returned all parameters to preoperative levels by 48 h postoperation, while non-burn patients showed a slower rate of return of platelets and factor V. This study suggests that burn patients may safely undergo re-operation at 48 h intervals for successive wound debridements if clinically necessary.

Original languageEnglish (US)
Pages (from-to)432-436
Number of pages5
JournalBurns
Volume21
Issue number6
DOIs
StatePublished - Sep 1995

ASJC Scopus subject areas

  • Surgery
  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

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